脑膜败血黄杆菌的临床分布及耐药性分析  

The clinical distribution and drug resistance of chryseobacterium meningosepticum

作　　者：何小帆[1] 陈慧红[1] 金敏雅[1] 余素飞[1] 

机构地区：[1]浙江省台州医院检验科,浙江台州317000

出　　处：《中国卫生检验杂志》2011年第2期432-433,共2页Chinese Journal of Health Laboratory Technology

基　　金：台州市科技计划项目(061KY51)

摘　　要：目的:了解我院脑膜败血黄杆菌的临床分布和耐药性。方法:对83株脑膜败血金黄杆菌常规细菌培养,采用法国生物梅里埃鉴定系统进行细菌鉴定,采用纸片扩散法(K-B法)进行抗生素药敏试验。结果:脑膜败血黄杆菌的科室分布以ICU为主(占70.0%),标本分布以痰液为主(占83.1%),脑膜败血金黄杆菌对米诺环素的耐药率最低为3.6%,对含酶抑制剂的复合制剂哌拉西林/他唑巴坦的耐药率为25.3%,对头孢哌酮/舒巴坦的耐药率为27.7%,其余抗菌药物的耐药率均超过50.0%。结论:脑膜败血黄杆菌对多种抗生素往往表现为高度耐药和多重耐药,对于该菌引发的医院内感染,临床要予以足够重视,应根据病情,参照药敏结果合理选择使用抗菌药物。Objective：To understand the clinical distribution and drug resistance of Chryseobacterium meningosepticum.Methods： The 83 Chryseobacterium meningosepticum strains were routine bacterial culture identification of bacteria was used by France BioMerieux identification system.The susceptibility test of bacteria were detected by Kirby-Bauer method.Results： Chryseobacterium meningosepticum infection mainly distributed at intensive care unit（ICU）（about 70.0%）,and which were mostly examinated from sputums（about 83.1%）.Whose drug resistance rate to minocycline was 3.6%,to piperacillin/tazobactam and cefoperazone/sulbactam was 25.3%,27.7% respectively,and to other antimicrobial was more than 50.0%.Conclusion： Chryseobacterium meningosepticum was the high resistant and multidrug resistant to polyantibiotic.It is important for selecting the antimicrobial drugs rationally according to illness state and susceptibility test results to treat Chryseobacterium meningosepticum infection.

关 键 词：脑膜败血金黄杆菌 医院感染 耐药性 

分 类 号：R378[医药卫生—病原生物学]