获得性免疫缺陷综合征患者戊型肝炎病毒感染状况  

The risk of HEV infection in patients with AIDS

作　　者：严艳[1] 李卓[1] 牛京勤[1] 郝娃[1] 殷继明[1] 

机构地区：[1]北京市卫生局肝炎研究所,北京100069

出　　处：《中国卫生检验杂志》2011年第2期442-443,共2页Chinese Journal of Health Laboratory Technology

摘　　要：目的:了解获得性免疫缺陷综合征患者中,戊型肝炎病毒感染状况。方法:采用酶联免疫吸附(ELISA)方法,对86份获得性免疫缺陷综合征患者血清,进行anit-HEVIgM和IgG的检测。结果:86例AIDS患者检测anti-HEVIgM阳性率为2.3%,anti-HEV IgG阳性率为9.3%,anti-HEV抗体总阳性率为11.6%。各组间T淋巴亚群,ALT、AST、TBIL比较差异并无统计学意义,(P>0.05)。结论:获得性免疫缺陷综合征人群中,HEV感染率略高于普通人群。Objective：To examine seroprevalence of HEV in persons with AIDS.Methods： We collected sera from 86 patients with HIV infection to detect the anti-hepatitis E virus antibody IgM and IgG by using an enzyme-linked immunosorbent assay and T lymphocyte by using flow cytometry.Results： The positive rate of anti-HEV IgM was 2.3% in the 86 patients,that of anti-HEV IgG was 9.3%.The total positive rate of anti-HEV was 11.6%.There were no significant difference in T lymphocyte subsets,ALT,AST and TBIL（P0.05）.Conclusion： The HIV-infected patients were at higher risk of HEV infection than normal people.

关 键 词：获得性免疫缺陷综合症 戊型肝炎病毒 T淋巴细胞亚群 

分 类 号：R512.91[医药卫生—内科学]