前列腺增生危险因素的病例对照研究  

Case-control study of the risk factors on benign prostatic hyperplasia

作　　者：冀楠[1] 李晋军[1] 漆咏梅[2] 

机构地区：[1]武汉科技大学医学院预防医学系,武汉430065 [2]武汉科技大学附属普仁医院病理科

出　　处：《公共卫生与预防医学》2011年第1期29-31,共3页Journal of Public Health and Preventive Medicine

摘　　要：目的研究前列腺增生(BPH)的各种危险因素及其危害程度。方法以132例病理确诊的前列腺增生患者为病例组,以年龄匹配的132例无前列腺增生患者为对照组进行1∶1配对病例对照研究。采集人口学因素、高血压史、糖尿病史、实验检测等临床资料。资料分析采用单因素和多因素条件Logistic回归分析。结果 (1)单因素分析显示:在吸烟、饮酒、糖尿病史、高血压史、慢性支气管炎史、肾囊肿史和慢性前列腺炎史差异统计学意义(P<0.05)。(2)多因素分析显示:吸烟(OR=0.530)、糖尿病史(OR=2.227)、高血压史(OR=1.862)、慢性前列腺炎(OR=2.414)是BPH的独立危险因素(P<0.05)。结论前列腺炎史、高血压史`、糖尿病史是BPH发病的危险因素,吸烟为保护性因素。良好的血压和血糖控制是预防BPH的重要方法。Objective To identify the risk factors and related degree associated to benign prostatic hyperplasia（BPH）.Methods A 1∶1 case-control study on 132 BPH patients were matched with 132 controls with non-BPH.Collection of demographic factors,history of hypertension,diabetes,laboratory indicators and other clinical data.Data were analyzed with conditional univariate and multivariate logistic regression analysis.Results（1）Single-factor analysis showed：the two groups were significantly different in smoking,drinking,history of hypertension,diabetes,chronic bronchitis,renal cysts and chronic prostatitis.（2）Multi-factor analysis indicated： smoking,history of diabetes,history of hypertension chronic prostatitis were independent risk factors of BPH.The ratio of the four factors for BPH were 0.530、2.227、1.862、2.414 respectively.Conclusions History of diabetes,hypertension,chronic prostatitis may be the risk factors of BPH.Smoking may be the preventive factors.The effective control of blood pressure and blood sugar are important ways to prevent benign prostatic hyperplasia.

关 键 词：前列腺增生 相关危险因素 病例对照研究 

分 类 号：R697.3[医药卫生—泌尿科学]