中药颈椎Ⅰ号治疗模拟颈神经根炎病理学观察  

Pathological Observation on the Treatment of the Imitative Cervical Radiculoneuritis with Chinese Medicinal Herbs Decoction Jingzhui No I

作　　者：张军[1] 孙树椿[1] 

机构地区：[1]中国中医研究院骨伤科研究所,北京100700

出　　处：《中国骨伤》1999年第6期13-15,共3页China Journal of Orthopaedics and Traumatology

摘　　要：目的　为了观察中药颈椎 号对模拟颈神经根炎的疗效及作用机理。方法　将 96只模拟颈神经根炎 Wistar大鼠随机分为 4组 :颈椎 号中剂量组、颈椎 号高剂量组、颈复康组及空白对照组 ,分别给予颈椎 号中剂量、高剂量、颈复康及凉开水 ,于造模后 3天、 7天、 14天、 4 2天 ,取神经根进行病理学观察。结果　颈椎 号中剂量、高剂量可以明显减轻模型鼠颈神经根的充血、水肿、淋巴细胞浸润等炎症反应 ,减轻成纤维细胞和胶原纤维的增多 ,减轻瘢痕化 ,促使神经功能恢复。结论　颈椎Objective To study the therapeutic effect of Chinese medicinal herbs decoction, Jingzhui No I(JZ Ⅰ) on imitative cervical radiculoneuritis and its mechanism Methods 96 Wistar rats were operated for modelling imitative cervical radiculoneuritis and then divided into 4 groups:moderate and high dosage JZ Ⅰ groups, orally given moderate dosage or high dosage of JZ Ⅰ once per day; Jingfukang (a eutherapeutic Chinese herbs in treating radiculoneuritis) group; and blank control group, given water only 3,7, 14 and 42 days after operation, the nerve roots were taken out for pathological observation Results The JZ Ⅰwith moderate and high dosages could obviously alleviate congestion, edema and lymphocyte infiltration of inflammatory reaction at 3 and 7 days after operation; and reduce the proliferation of fibroblasts and collagen fibers, thus reducing cicatrization of the nerve roots at 14 and 42 days after operation Conclusion JZ Ⅰcan alleviate inflammatory reaction, inhibit cicatrization, and promote the recovery of nerve function It is an effective drug in treating imitative cervical radiculoneuritis

关 键 词：中药颈椎I号 颈神经根炎 病理学 中医药疗法 

分 类 号：R277.754.9[医药卫生—中医学]