^(18)F-FDG PET/CT在颈部肿块中的应用价值  

Value of ^(18)F-FDG PET/CT in cervical lumps

作　　者：郭佳[1] 陈跃[1] 黄占文[1] 张春银[1] 蔡亮[1] 张莉[1] 

机构地区：[1]泸州医学院附属医院核医学科,四川泸州646000

出　　处：《重庆医学》2011年第8期760-761,763,I0002,共4页Chongqing medicine

基　　金：2008年四川省卫生厅四川省医学重点学科建设资助项目(2008-17)

摘　　要：目的探讨18F-脱氧葡萄糖正电子发射体层摄影术(FDG PET)/CT显像在颈部肿块中的应用价值。方法回顾性分析30例以颈部肿块就诊患者的18F-FDG PET/CT显像资料,对所有患者行病理检查或临床随诊,并将结果与PET/CT显像结果进行比较。结果 30例患者中PET/CT显像发现可疑恶性病变或既往恶性肿瘤转移27例,其中假阳性3例。另3例PET/CT显像只见颈部淋巴结肿大而无葡萄糖代谢,诊断为良性。PET/CT显像对颈部肿块恶性病因检出的灵敏度、特异性、准确性、阳性预测值及阴性预测值分别为88.9%(24/27)、100%(3/3)、90%(27/30)、100%(24/24)和50%(3/6)。结论 18F-FDG PET/CT显像在明确颈部肿块病因中的应用有积极意义,但颈部肿块中良性病变亦较多,应密切结合全面的临床资料进行分析。Objective To evaluate the value of ^18F-FDG PET/CT in cervical lumps to identify the primary disease.Methods30 patients with cervical lumps were included and underwent whole body ^18F-FDG PET/CT imaging to search the causes.The results of PET/CT imaging were based on pathologic examination and clinical follow-up.ResultsThere were 27 positive cases,but 3 in 27 were false positive.The other 3 cases were proved true negative.The sensitivity,specificity,accuracy,positive predictive value and negative predictive value obtained by 18F-FDG PET/CT in diagnosing malignant primary lesions were 88.9%（24/27）,100%（3/3）,90%（27/30）,100%（24/24） and 50%（3/6）,respectively.Conclusion^18F-FDG PET/CT is useful to detect the primary lesions and staging for malignancy.But benign masses occupy some percentage in cervical lumps,so detailed clinical data is very important.

关 键 词：体层摄影术 发射型计算机 体层摄影术 X线计算机 颈部肿块 颈淋巴结转移癌 脱氧葡萄糖 

分 类 号：R816.3[医药卫生—放射医学]