基于现代文献的艾滋病中医证候规律研究  

Study on the Syndrome Law of AIDS Based on Modern Literature

作　　者：王勇[1] 谢世平[1] 梁润英[1] 郭选贤[1] 闫国立[1] 李丹[1] 施淼[1] 薛敏[1] 郭晓辉[1] 

机构地区：[1]河南中医学院艾滋病研究所河南省病毒性疾病重点研究室,河南郑州450008

出　　处：《中医学报》2011年第2期129-131,共3页Acta Chinese Medicine

基　　金：国家"十一五"科技攻关项目(编号:2900ZX10005-02);国家973课题(编号:2006CB504802);国家自然科学基金(编号:90409004)

摘　　要：目的:探讨艾滋病中医理论文献和临床文献中的证候规律、发病机制,为临床研究和实验研究提供依据。方法:检索相关文献,以证为中心对文献进行提取。建立Excel数据表,并对提取数据进行统计分析。结果:艾滋病所涉及的证型、证素和症状数据显示艾滋病临床证候以虚证为多,分布较为分散;病位集中在肺、脾(胃)、肾等;病机为气虚、火(热)、湿、阴虚、毒、痰、血瘀、阳虚等;艾滋病常见症状为发热、神疲乏力、腹泻、消瘦、食欲减退、脉细等。其证候分型概括为脾气虚证、肺气虚证、气虚血瘀证、脾虚湿浸证、气阴两虚证、痰热壅肺证等。结论:艾滋病临床证候复杂多样,虚实错杂,以虚证为多。艾滋病证候的规律和特点反映了其本虚标实、阴阳失调、虚实夹杂的基本病机,提示艾滋病发病具有正气亏虚、邪毒入侵、脏腑受损、瘀血阻络、湿热内蕴等病理机制。Objective：To evaluate the syndrome law and pathogenesis of AIDS in the theoretical and clinical literature of traditional Chinese medicine,thus providing evidence for the clinical and experimental research.Methods：To search related literature for the extraction of the literature with syndrome as the center.Create Excel data tables,and extract data for statistical analysis.Results：The syndromes,syndrome elements and symptom data involved by AIDS showed that the clinical syndrome of AIDS was mainly deficiency syndrome with dispersed distribution;disease location was concentrated in lung,spleen（stomach） and Kidney,etc;pathogenesis was Qi deficiency,fire（heat） pathogen,dampness pathogen,Yin deficiency,toxins,phlegm,blood stasis,Yang deficiency,etc.;the common symptoms of AIDS were fever,fatigue,diarrhea,emaciation,anorexia,etc.The syndromes were as follows,spleen-qi deficiency syndrome,spleen deficiency and dampness stagnation,liver and kidney deficiency,phlegm heat obstructing the lung and so on.Conclusion：The clinical syndromes of AIDS are complex and diverse with deficiency syndrome mingling with excess syndrome and dominated by deficiency syndrome.The law and characteristics of AIDS syndromes reflect that the basic pathogenesis is asthenia in origin and asthenia in superficiality,imbalance of Yin and Yang and deficiency syndrome mingling with excess syndrome,suggesting that the onset of AIDS has the pathological mechanism of healthy-qi deficiency,impairment of zang and fu organs,blood stasis and obstruction of damp-heat inside.

关 键 词：艾滋病 文献研究 证候研究 证素 因子分析 

分 类 号：R259.129.1[医药卫生—中西医结合]