清远市区企业职工乙型病毒性肝炎血清流行病学分析  

Epidemiological Analysis of Hepatitis B among Enterprise Employees in Qingyuan City

作　　者：罗文玲[1] 黄旭[1] 陈文青[1] 陈丽萍[1] 曹晓月 朱杏群 汤炜[1] 刘皑莹 许倩[1] 袁俊[1] 

机构地区：[1]广东省清远市疾病预防控制中心微生物检验科,511515

出　　处：《职业与健康》2011年第5期536-537,共2页Occupation and Health

摘　　要：目的了解清远市区企业职工乙型病毒性肝炎(乙肝)的流行情况,为乙肝的防治工作提供依据。方法 2009年1—12月,采用整群抽样的方法,分批对清远市区的10家企业的职工进行职业健康检查并同时抽取静脉血样,用酶联免疫吸附试验(ELISA方法)进行乙肝病毒血清学检测。结果共检测血样9 850份,HBsAg、HBsAb、HBeAg、HBeAb、HBcAb总体阳性率分别为5.62%、63.81%、0.63%、9.72%、11.74%,其中HBsAg阳性率男性职工(6.80%)高于女性职工(4.03%),国企职工(7.17%)高于外企职工(4.52%)(均P<0.01)。HBsAb阳性率女性职工(66.86%)高于男性职工(61.57%),国企职工(66.31%)高于外企职工(62.03%)(均P<0.01);乙肝5项标志物检测,HBV总感染率为71.08%,单项HBsAb阳性率为58.79%,"大三阳"阳性率为0.60%,"小三阳"阳性率为3.77%,HBV感染全阴率为28.92%。结论清远市区企业职工HBV感染情况不容乐观,应继续加强乙肝疫苗的接种工作,加强乙肝防治工作,控制乙肝流行。[Objective]To understand the prevalence of hepatitis B among enterprise employees in Qingyuan city,and to provide scientific basis for its prevention and control. [Methods]During 2009,employees from 10 enterprises in urban Qingyuan received occupational health examination,and their blood samples were collected.ELISA method was adopted for hepatitis B virus（HBV） serological detection. [Results]Of 9 850 blood samples,the total positive rate of HBsAg,HBsAb,HBeAg,HBeAb,HBcAb was 5.62%,63.81%,0.63%,9.72%,11.74%,respectively,among which HBsAg positive rate of male（6.80%） was higher than that of female（4.03%）,state-owned enterprise employees（7.17%） was higher than overseas-invested enterprise employees（4.52%）（both P20.01）.HBsAb positive rate of female workers（66.86%） was higher than that of male workers（61.57%）,state-owned enterprise employees（66.31%） was higher than overseas-invested enterprise employees（62.03%）（both P0.01）.Detection of hepatitis B 5 markers showed total infection rate of HBV was 71.08%,58.79% of single HBsAb positive rate, 0.60% of HBV-marker modes of HBsAg＋,HBeAg＋,HBcAb＋,3.77% of HBV-marker modes of HBsAg＋,HBeAb＋,HBcAb＋,28.92% of HBV negative. [Conclusion]The infection status of HBV among enterprise employees of urban Qingyuan is not optimistic.It is necessary to continue to strengthen hepatitis B vaccination,to strengthen prevention and control of hepatitis B,and to control hepatitis epidemic.

关 键 词：肝炎 乙肝 抗原 抗体 

分 类 号：R181.3[医药卫生—流行病学]