A novel strategy for immobilization of thionine based on calcium carbonate-gold nanoparticles inorganic hybrid composite and its application in hydrogen peroxide sensor  

作　　者：LI Feng FENG Yan LI JingJing GUO Jie 

机构地区：[1]Key Laboratory of Eco-Chemieal Engineering, Ministry of Education College of Chemistry and Molecular Engineering, Qingdao University of Science and Technology, Qingdao 266042, China [2]Department of Radiotherapy, Second Hospital, Jilin University, Changchun 130025, China

出　　处：《Science China Chemistry》2011年第3期545-551,共7页中国科学（化学英文版）

基　　金：supported by the National Natural Science Foundation of China(20775039)

摘　　要：A novel strategy for efficient immobilization of electroactive Thionine(Th)on the gold(Au)electrode surface based on calcium carbonate-gold nanoparticles(CaCO3-AuNPs)inorganic hybrid composite was proposed and conducted by the strong electrostatic interaction between positively charged Th and negatively charged CaCO3-AuNPs composite.The hybrid composite was obtained by the adsorption of AuNPs onto the surface of CaCO3 microspheres through electrostatic interaction.Due to the microporous architecture,large surface area,and good biocompatibility of CaCO3-AuNPs composite,the amount and stability of the immobilized Th were highly strengthened.The application of the resulting Th modified electrode in the hydrogen peroxide(H2O2)sensor was also investigated.It exhibited rapid response to H2O2 within 3 s.The linear calibration ranged from 8.00×107to 1.06×10 -3mol/L with a detection limit of 2.00×10 -7mol/L.A novel strategy for efficient immobilization of electroactive Thionine（Th）on the gold（Au）electrode surface based on calcium carbonate-gold nanoparticles（CaCO3-AuNPs）inorganic hybrid composite was proposed and conducted by the strong electrostatic interaction between positively charged Th and negatively charged CaCO3-AuNPs composite.The hybrid composite was obtained by the adsorption of AuNPs onto the surface of CaCO3 microspheres through electrostatic interaction.Due to the microporous architecture,large surface area,and good biocompatibility of CaCO3-AuNPs composite,the amount and stability of the immobilized Th were highly strengthened.The application of the resulting Th modified electrode in the hydrogen peroxide（H2O2）sensor was also investigated.It exhibited rapid response to H2O2 within 3 s.The linear calibration ranged from 8.00×107to 1.06×10 -3mol/L with a detection limit of 2.00×10 -7mol/L.

关 键 词：THIONINE CaCO3-AuNPs SENSOR electrostatic interaction 

分 类 号：O613.3[理学—无机化学] TB383[理学—化学]