Characteristics of newly-formed cementum following emdogain application  

作　　者：Khalid Al-Hezaimi Mansour Al-Askar Abdulaziz Al-Rasheed 

机构地区：[1]Eng.A.B.Bagshan Growth Factors and Bone Regeneration Research Chair, King Saud University,Riyadh,Saudi Arabia [2]Department of Periodontology,School of Dentistry, King Saud University,Riyadh, Saudi Arabia [3]Eng.A.B.Bagshan Growth Factors and Bone Regeneration Research Chair, King Saud University,Riyadh, Saudi Arabia [4]Department of Periodontology,School of Dentistry, King Saud University,Riyadh,Saudi Arabia

出　　处：《International Journal of Oral Science》2011年第1期21-26,共6页国际口腔科学杂志（英文版）

基　　金：supported by grant from Eng.A.B.Growth Factors and Bone Regeneration Research Chair and number #LR0003

摘　　要：Periodontal regenerative techniques have been proposed; however, the outcomes remain debatable. The present investigation assessed the regenerated cementum following enamel matrix derivative application in dehiscence-type defects. Buccal osseous dehiscences were surgically created on the maxillary cuspid, and the second and fourth premolars in five female beagle dogs. The treatment group （n=15 sites） received the enamel matrix derived application, whereas the control groups （n=15） did not. The dogs were sacrificed 4 months following treatment and the specimens were histologically and histometrically examined. The newly formed cementum was uneven in thickness and mineralization, overlapped the old cementum and exhibited functional orientation, cementocyte lacunae and collagen fibril bundles. Most of the histological specimens showed the presence of a gap between the newly formed cementum and the underlying dentin. Control sites did not exhibit any cementum formation. The present study concluded that newly formed cementum is of cellular type and exhibits multiple characteristics.Periodontal regenerative techniques have been proposed; however, the outcomes remain debatable. The present investigation assessed the regenerated cementum following enamel matrix derivative application in dehiscence-type defects. Buccal osseous dehiscences were surgically created on the maxillary cuspid, and the second and fourth premolars in five female beagle dogs. The treatment group （n=15 sites） received the enamel matrix derived application, whereas the control groups （n=15） did not. The dogs were sacrificed 4 months following treatment and the specimens were histologically and histometrically examined. The newly formed cementum was uneven in thickness and mineralization, overlapped the old cementum and exhibited functional orientation, cementocyte lacunae and collagen fibril bundles. Most of the histological specimens showed the presence of a gap between the newly formed cementum and the underlying dentin. Control sites did not exhibit any cementum formation. The present study concluded that newly formed cementum is of cellular type and exhibits multiple characteristics.

关 键 词：REGENERATION CEMENTUM enamel matrix protein 

分 类 号：R78[医药卫生—口腔医学]