维持性血液透析患者抑郁状态与MIA综合征各组分的关系  

Relations of Depression and MIA Syndrome among Maintenance Hemodialysis Patients

作　　者：徐大宇[1] 孔祥雷[1] 唐利军[1] 许冬梅[1] 

机构地区：[1]山东大学附属千佛山医院肾内科,山东济南250014

出　　处：《医学与哲学（B）》2011年第2期39-40,64,共3页Medicine & Philosophy(B)

摘　　要：探讨血液透析患者抑郁的发生率及与营养不良、炎症、动脉粥样硬化的关系。采用Zung抑郁自评量表、改良主观全面营养评价法、颈动脉内中膜厚度(I MT)、hsCRP、血白蛋白、血红蛋白等对57例血液透析患者进行评估。根据SDS分值将患者分为抑郁组和对照组,分别进行炎症、营养不良和动脉粥样硬化比较。抑郁组患者19例(33.3%),hs-CRP、营养不良评分、I MT值明显高于对照组,血清白蛋白、血红蛋白明显低于对照组。Pearson相关分析显示SDS分值与hs-CRP、营养不良评分、I MT值显著正相关。因此,血液透析患者抑郁发生率高,与营养不良、炎症、动脉粥样硬化关系密切,应注意抑郁状态的评估。To investigate the relations of depression and MIA syndrome among Hemodialysis patients. Fifty seven patients with ESRD were evaluated the depression status using Self--Rating Depression Scale, the nutrition status by Modified Subjective Global Assessment of Nutrition and the atherosclerosis by intima media thickness （IMT）. The biochemical parame- ters including hsCRP, Alb, Hb,SCr and BUN were measured in ESRD patients. The patients were divided into depression group and control group to compare with the level of hsCRP, malnutrition score, IMT and other biochemical parameters. Nineteen patients （ 33.3 % ）had depression. The mean values of hs--CRP, MS and IMT in the depression group were signif- icantly greater than those in control group. The levels of serum Alb and Hb were significantly lower than those in control group. The SDS scale showed a significant positive correlation with MS, hs--CRP and IMT. Depression is observed highly in MHD patients, which is related closely to malnutrition, inflammation and atherosclerosis. The MHD patients should be e valuated for depression status.

关 键 词：抑郁 血液透析 营养不良 炎症 动脉粥样硬化 

分 类 号：R395.1[哲学宗教—心理学]