心肌酶谱与肌钙蛋白I测定在急性心肌梗死早期诊断中的临床价值  

Clinical value of early diagnosis of myocardial enzymes and cTnI determination in acute myocardial infarction

作　　者：周化汤 高思安[1] 

机构地区：[1]浏阳市人民医院检验科,湖南浏阳410300

出　　处：《现代医药卫生》2011年第5期654-655,共2页Journal of Modern Medicine & Health

摘　　要：目的:探讨心肌酶谱和肌钙蛋白I(cTnI)测定在急性心肌梗死(AMI)早期诊断中的临床应用价值。方法:采用日立7600-020全自动生化分析仪及诊断试剂盒,检测了87例AMI患者心肌酶谱(AST、LDH、CK.、CK-MB)和cTnI,并比较其特异性和敏感性。结果:87例AMI患者血清cTnI、CK、CK-MB、AST、LDH水平与正常对照组比较差异均有非常显著性(P<0.01),87例AMI患者中,75例心肌酶谱升高,82例肌钙蛋白I阳性,敏感性分别为86.2%、94.3%;特异性分别为92.0%、96.0%。结论:心肌酶谱与cTnI测定在AMI早期诊断中具有重要的临床价值。Objective：To investigate the clinical value of myocardial enzymes and troponin I（cTnI） measurement in the diagnosis of acute myocardial infarction（AMI）.Methods：Hitachi 7600-020 automatic biochemical analyzer and diagnostic kits were used to detect myocardial enzymes（AST,LDH,CK,CK-MB） and cTnI in 87 cases of AMI for comparing their specificity and sensitivity.Results：cTnI,CK,CK-MB,AST,LDH levels in 87 cases of AMI had significant difference compared with the control group（P0.01）.Among 87 cases,myocardial enzymes were increased in 75 cases,cTnI was positive in 82 cases.The sensitivities were 86.2% and 94.3%,the specificities were 92.0% and 96.0% respectively.Conclusion：The determination of myocardial enzymes and cTnI has important clinical value in the early diagnosis of acute myocardial infarction.

关 键 词：心肌酶谱 肌钙蛋白I 急性心肌梗死 

分 类 号：R446[医药卫生—诊断学]