结核病五项实验检测方法的对比分析  

The evaluation of 5 laboratory detection methods on the diagnosis of tuberculosis

作　　者：闫国蕊[1] 腊胜明[2] 杨建华 王国斌[1] 叶德普[1] 彭义利[1] 

机构地区：[1]河南省结核病防治研究所,450003 [2]河南省医学科学研究所 [3]焦作市结核病防治所

出　　处：《中国防痨杂志》1999年第3期165-166,共2页Chinese Journal of Antituberculosis

摘　　要：目的　对实验检测方法进行对比分析，探讨对结核病诊断的价值。方法　选健康人５３ 名、肺结核７０ 例及非结核肺部疾患３０ 例，采用痰涂片、培养、结明试验、酶联免疫法及聚合酶链反应检测进行对比分析。结果　涂片、培养、酶联免疫法特异性高，但敏感性低于５０ ％ ，其次为聚合酶链反应法，结明试验特异性与敏感性分别为９８１ ％ 及６４２ ％ 。结论　结明试验具有特异性高、简便、快速等特点，是结核病诊断的一种有力辅助手段。Objective To analyse and co mpare 5 laboratory dectection methods and try evaluate the effect ondiagnosis of tuberculosis . Methods 53 health persous .70 pulm .tuberculosis cases and 30 cases with non tuberculo sis disease were studies and using sputu m sm ear ,culture , Myco Dot test , P C R, E L I S A assay ,all results were co m pared . Results The studies sho wed that smear ,culture , E L I S A had high sensitivity but the specificity are belo w50 % ,and then the P C R assay . Conclusion Myco Dot have high specificity ,simple and convenient ,rapid superiori ty ,this assay may be the m ore valuable auxiliary test on diagnosis of tuberculosis .

关 键 词：实验室检测 结核病 诊断 

分 类 号：R520.4[医药卫生—内科学]