血清中抗幽门螺杆菌-IgG抗体母婴垂直传播的研究  

Study on the Vertical Spread from Mother to Infant Through Detection of specific IgG against Helicobacter Pylori in Human Serum

作　　者：何长华[1] 陈有荣[1] 马理[1] 吴波[1] 吴宏安[1] 刘晓清 

机构地区：[1]湖北省荆州市第一人民医院消化科,荆州434000

出　　处：《医学新知》1999年第3期122-123,共2页New Medicine

摘　　要：为探讨血清中抗幽门螺杆菌－IgG抗体能否母婴垂直传播，采集产妇临产前静脉血标本，婴儿出生时从脐静脉抽血标本后再剪断脐带，采用间接ELISA法测定血清中抗Hp抗体。结果显示78例婴儿血清中抗Hg－IgG抗体检测阳性者28例，其母亲均为阳性；产妇为阴性者，其婴儿均为阴性。上述结果提示：母体血清中抗Hg－IgG抗体能够通过胎盘进入婴儿血液，即能够垂直传播。To investigate whether specific IgG against Helicobacter pylor: (H' pylori)in human serum can be vertical spread from mother to infant. Methods blood specimens were taken from seventy eight puerperants' veins before they were giving birth to child, and from their babies' umbilical veins just before cutting off their umbilical cord which was used to detect the specimens whether helicobacter pylori enzyme exist. Immunoassay kit, afforded by general investigation and coorporation unit about H- pylori infection of Shanghal digestve soclety. Results There were twenty eight babies whose specific IgG against H' pylori were positive, their mother's specific IgG against H' pylori were positive too' The puerperants' specific IgG against H' pylori were negative,their babies' antibody were negative too, Conclution the results suggest that the specific IgG agalnst H' pylori ln mother's blood serum can enter infants blood through placenta,as it were, it can vertical spread'

关 键 词：幽门螺杆菌 IGG 抗体 母婴垂直传播 

分 类 号：R378.99[医药卫生—病原生物学] R573.01[医药卫生—基础医学]