非典型病原体混合感染的诊断和治疗  

Diagnosis and treatment of mixed infection with atypical pathogens and bacteria.

作　　者：印洁[1] 施毅[1] 

机构地区：[1]南京军区南京总医院呼吸科,南京210002

出　　处：《中国实用内科杂志》2011年第3期236-238,共3页Chinese Journal of Practical Internal Medicine

摘　　要：非典型病原体是中国社区获得性肺炎(CAP)的主要致病原之一,可以在所有年龄段人群中引起轻-中度疾病,而非典型病原体与细菌的混合感染与较高的病死率相关。在确定非典型病原体感染的基础上,如果患者同时有细菌感染的相应临床表现,呼吸道分泌物细菌培养阳性,可以考虑非典型病原体混合感染。临床在经验性治疗CAP时,如果不能排除非典型病原体混合感染,应选择抗菌谱可覆盖非典型病原的药物单用或联合应用。Atypical pathogens are one of major causes of community acquired pneumonia （CAP） in China, and may contribute to mild to moderate disorders among all age groups. Mixed infection with atypical pathogens and bacteria seems to be correlated with higher mortality. In cases where infection with atypical pathogens is identified,mixed infections of atypical pathogens and bacteria could be considered if the patient also has the corresponding clinical signs and symptoms of bacterial infection and positive bacterial culture of respiratory secretions. For clinical empirical treatment of CAP, if atypical pathogens infection cannot be excluded, antimicrobial drugs which cover the atypical pathogens spectrum should be used alone or in combination with others.

关 键 词：非典型病原体 支原体肺炎 衣原体肺炎 军团菌肺炎 社区获得性肺炎 

分 类 号：R5[医药卫生—内科学]