双咪唑鎓盐催化苯偶姻缩合反应的研究  

The Catalytic Activity Researches of Bisimidazolium Salts in Benzoin Condensation Reaction

作　　者：李鹏熙[1] 蒋宗林[1] 王心良[1] 杨玲玲[1] 霍娜[1] 马丽霞[1] 

机构地区：[1]西华师范大学化学化工学院,四川南充637009

出　　处：《西华师范大学学报（自然科学版）》2011年第1期80-84,共5页Journal of China West Normal University(Natural Sciences)

基　　金：西华师范大学科研项目启动基金(05B031);西华师范大学大学生科技创新基金项目(42710066)

摘　　要：设计合成了一种新型的双咪唑鎓盐,研究了该双咪唑鎓盐催化苯甲醛合成苯偶姻的安息香缩合反应,考察了溶剂,催化剂用量、反应温度、碱的用量及不同底物对该反应的影响.结果表明:双咪唑鎓盐3能有效地催化苯偶姻缩合反应,且反应的最佳条件:温度为60℃,催化剂用量为2mmol%,50%NaOH/H2O(4.0equiv.)作碱、THF作溶剂,化学产率最高可达75%.A new method for synthesis of benzoin was achieved by the condensation of benzaldehyde in the presence of bisimidazolium salts as the catalysts.The effects of bisimidazolium salts,the different amount of catalyst,the reaction temperature and the reaction time on the benzoin condensation of benzaldehyde were investigated.Results showed compounds 3 was the best catalyst.Benzoin could be obtained in 75% yield and the reaction was performed at 60℃,with catalyst 2mmol%,50% NaOH/H2O（4.0equiv.） solution as base,THF as solvent.

关 键 词：咪唑鎓 苯偶姻 催化 苯甲醛 合成 

分 类 号：O626.23[理学—有机化学]