雌鼠妊娠期手机辐射对仔鼠学习记忆影响  

Effect of electromagnetic radiation of cell phone on learning and memory of offspring rats with maternal exposure

作　　者：张静[1] 王秋丽[1] 刁飞燕[1] 廉志顺[1] 郭冬梅[1] 崔晞[1] 

机构地区：[1]山东大学公共卫生学院卫生检验研究所,山东济南250012

出　　处：《中国公共卫生》2011年第3期291-292,共2页Chinese Journal of Public Health

基　　金：山东省自然科学基金(Y2007C086)

摘　　要：目的研究妊娠期接受手机辐射对仔鼠学习记忆的影响。方法孕鼠经不同强度手机辐射后,测定新生鼠脑组织乙酰胆碱酯酶(AChE)活力,应用Morris水迷宫测试幼鼠学习记忆能力。结果与对照组比较,AChE活力升高,其中高、中强度辐射组(0.55±0.20)、(0.51±0.14)U/mgprot与对照组(0.33±0.22)U/mgprot比较,差异有统计学意义(P<0.05);定位航行实验,第2、3d,高、中强度辐射组平均潜伏期分别为(63.9±12.2)、(66.6±20.4)和(55.1±20.5)、(53.3±16.8)s,与对照组(36.2±13.6)、(32.9±16.5)s比较,明显延长,差异有统计学意义(P<0.05),第4 d,各辐射组平均潜伏期均长于对照组,差异有统计学意义(P<0.05);高强度辐射组穿越原平台区次数低于对照组,差异有统计学意义(P<0.05)。结论妊娠期接受手机辐射对仔鼠学习记忆能力有一定损害。Objective To investigate the effect of maternal cell phone electromagnetic radiation exposure on learning and memory ability of offspring rats.Methods Pregnant rats were radiated with cell phone electromagnetic radiation of different intensity.Then the activity of acetylcholine esterase（AChE） in newborn rats＇ brain tissue was tested and Morris water maze was used to determine the learning and memory ability of the offspring rats.Results Significant increase of AChE activity was detected after the radiation among the rats of high（0.55±0.20 U/mg·prot） and moderate intensity group（0.51±0.14 U/mg·prot） compared to that of the control group（0.33±0.22 U/mg·prot,P0.05 for all）.Significant differences in place navigation were found at the second and third day of the radiation among the high（63.9±12.2,66.6±20.4s） and moderate intensity group（55.1±20.5,53.3±16.8s） compared to those of the control group（36.2±13.6,32.9±16.5s,P0.05 for all）.At the fourth day,significant differences were found in place navigation among the rats of four groups（P0.05）.The offspring rats in high intensity group showed less times of crossing over the target area than those in control group with a significant difference（P0.05）.Conclusion Exposure to electromagnetic radiation from cell phone during pregnancy has harm effects on learning and memory ability of offspring rats.

关 键 词：手机辐射 仔鼠 学习记忆 乙酰胆碱酯酶 MORRIS水迷宫 

分 类 号：R144.1[医药卫生—公共卫生与预防医学]