黄体酮与消旋山莨菪碱治疗输尿管结石的疗效比较  

Comparison of Clinical Efficacy of Progesterone vs. Racanisodamine in the Treatment of Ureteral Calculus

作　　者：王平[1] 肖昌录 陈荟旭[1] 罗鹏[2] 

机构地区：[1]四川邛崃市医疗中心医院药剂科,邛崃市611530 [2]四川邛崃市医疗中心医院泌尿科,邛崃市611530

出　　处：《中国药房》2011年第12期1094-1095,共2页China Pharmacy

摘　　要：目的:比较黄体酮与消旋山莨菪碱治疗输尿管结石的疗效。方法:选择符合标准的病例70例,将其随机均分为2组,试验组采用黄体酮注射液40mg,im,qd;对照组采用消旋山莨菪碱注射液10mg,im,qd。均用5%葡萄糖氯化钠注射液1000～1500mL中,i.v.gtt,每分钟60滴,余100mL时加入呋塞米注射液20mg。结果:试验组显效率、有效率、总有效率分别为82.86%、8.57%、91.43%,对照组分别为71.43%、8.57%、80.00%,2组比较均有显著性差异(P<0.01)。试验组第2个疗程内有1例女性患者出现轻度月经紊乱,对照组有2例轻度口干,治疗终止后均自行恢复。结论:黄体酮治疗输尿管结石疗效确切,无损伤。To compare the clinical efficacy of progesterone vs. racanisodamine in the treatment of ureteral calculus. METHODS： 70 patients meeting the criteria were randomly assigned into 2 groups with each group of 35 cases. Experimental group received Progesterone injection 40 mg, im, once a day. Control group received Racanisodamine injection 10 mg, ira, once a day. Both groups were treated with 5% Glucose injection 1 000-1 500 mL, i.v.gtt 60 drops.min^-1. Furosemide injection 20 mg was added into solution when Glucose injection 100 mL remained. RESULTS： The markedly effective rate, effective rate and total effective rate of experimental group were 82.86% , 8.57% and 91.43% , and those of control group were 71.43% , 8.57% , 80.00%. There were no significant difference between 2 groups （P〈0.01）. Slight menstrual disorder of 1 female patients was found in experimental group during 2 treatment courses while disappeared after treatment. 2 cases of slight dryness of the mouth were found in control group. CONCLUSION： Progesterone is effective and safe in the treatment of ureteral calculus.

关 键 词：黄体酮 山莨菪碱 输尿管结石 

分 类 号：R983.2[医药卫生—药品]