抗癌扶正方及含药血清对人肝癌细胞SMMC-7721生长的抑制作用  

Inhibiting effect of Kangai Fuzheng Prescription(KFP) on human hepatoma cell SMMZ-7721

作　　者：叶丽红[1] 皮文霞[1] 程海波[1] 张旭[1] 吴勉华[1] 章永红[1] 

机构地区：[1]南京中医药大学,南京210029

出　　处：《中华中医药杂志》2011年第3期588-591,共4页China Journal of Traditional Chinese Medicine and Pharmacy

基　　金：国家科技支撑计划(No.2006BAI11B08);江苏省自然科学基金项目(No.BK2007240)~~

摘　　要：目的:探讨抗癌扶正方的抗肝癌作用。方法:提取抗癌扶正方,使用药物及含药血清,针对人肝癌细胞SMMC-7721,经过细胞培养,分光光度计检测抗癌扶正方对肝癌细胞生长抑制率的影响。结果:抗癌扶正方及药物血清,具有良好的抑肝癌细胞生长作用,尤以1、10mg/mL剂量组效果最佳,作用程度与化疗药物类似。结论:抗癌扶正方能够抑制人肝癌细胞SMMC-7721活性。其机制有必要进一步深入探讨。Objective： Probing the anticancer effect of Kangai Fuzheng Prescription（KFP） which is from national experienced expert.Methods： Applying KFP,its pharmacological serum and human hepatoma cell of SMMZ-7721 to cell experiment,detecting the growth inhibiting rate.Results： It was shown that KFP and pharmacological serum can inhibit human hepatoma cell of SMMZ-7721.The better dosage groups were 1mg/ml,10mg/ml,while their efficacy was similar as that of chemotherapy.Conclusion： KFP could inhibit human hepatoma cell of SMMZ-7721.The mechanism needed further research.

关 键 词：抗癌扶正方 含药血清 人肝癌细胞SMMC-7721 生长抑制率 

分 类 号：R285.5[医药卫生—中药学]