6例危重甲型H1N1流感救治体会  

Experience in treatment of six critically ill cases with novel influenza A(H1N1)

作　　者：王静宜[1,2] 杜钟珍[2] 李建国[2] 韩骏峰 张学丽[2] 

机构地区：[1]天津医科大学,天津300070 [2]天津海河医院,天津300350

出　　处：《临床肺科杂志》2011年第4期515-516,共2页Journal of Clinical Pulmonary Medicine

摘　　要：目的探索危重甲型H1N1流感的救治方案。方法对6例危重甲型H1N1流感的临床特征、救治方案、预后进行回顾性分析。结果 6例患者中男4例,女2例,中位数年龄40岁。首发症状发热3例,咳嗽咳痰3例;5例最高体温在39.0℃以上;6例患者中3例有基础疾病;6例患者均使用奥司他韦、有创机械通气、甲强龙、低分子肝素钙治疗,4例使用CRRT治疗;6例患者中3例死亡、3例治愈。结论危重甲型H1N1流感病例的治疗,以抗病毒、改善氧合、减轻炎症反应为主的综合治疗。CRRT、ECMO等技术的使用会提高抢救的成功率。Objective To explore the clinic treatment of critically ill cases with novel influenza A（H1N1）.MethodsThe clinical characteristics,treatments and prognosis of 6 critically ill cases with novel influenza A（H1N1）,were analyzed retrospectively.Results4 male,2 female;median age 40 years;first sympotem was fever in 3 patients,in another 3 patients were cough.In 5 patients,temperature was more than 39℃.3 patients had chronic medical conditions.All 6 patients received oseitamivir,mechanical ventilation,methylprednisolone,low molecular weight heparin calcium.4 cases received continuous renal replacement therapy.In all 6 cases,3 cases were cured,and 3 cases died.Conclusionthe treatment with critical novel influenza A（H1N1） case should be a comprehensive treatments incluld antivirus,improving oxygenation function,attenuating inflammatory response.extracorporeal membrane oxygenation and continuous renal replacement therapy perhaps increase the success rate of rescue.

关 键 词：甲型H1N1流感 危重 治疗 

分 类 号：R511.7[医药卫生—内科学]