新疆伊犁地区哈萨克族人群代谢综合征及外周动脉疾病的相关性研究  

Relationship between peripheral artery disease and metabolic syndrome among Kazakh adults lived in Xinjiang Yili prefecture

作　　者：彭潇[1] 马依彤[1] 杨毅宁[1] 刘芬[1] 付其彦[1] 谢翔[1] 

机构地区：[1]新疆医科大学第一附属医院心脏中心,乌鲁木齐830011

出　　处：《中华全科医师杂志》2011年第3期178-182,共5页Chinese Journal of General Practitioners

基　　金：基金项目：新疆维吾尔自治区重大科技专项课题（200733146-3）

摘　　要：目的 了解新疆伊犁地区哈萨克族人群代谢综合征（MS）及外周动脉疾病（PAD）的患病情况,并探讨MS合并PAD的相关危险因素.方法 2007年10月至2009年6月,应用四阶段整群随机抽样法,在全疆23个市、7个地区、5个自治州抽取乌鲁木齐市、克拉玛依市、阜康市、吐鲁番地区、和田地区、伊犁哈萨克自治州等6个地区年龄35岁以上样本,男女均衡,选取其中新疆伊犁哈萨克自治州样本进行调查.所有调查者接受问卷调查、体格检查、相关生化指标及踝臂指数（ABI）的测定,统计MS及PAD的患病率.将PAD患者按是否合并MS分为MS组及非MS组,并分析哈萨克族人群PAD与MS危险因素的相关性.结果 调查有效样本1365人,MS的总患病率为23.7%,其中男性及女性的患病率分别为30.4%和19.0%;PAD总患病率为9.4%,男性及女性分别为7.0%和11.0%.MS组PAD患者平均年龄明显高于非MS组（t=5.348,P＜0.01）,且PAD合并MS发病与性别（男性）、年龄、收缩压、舒张压及血糖有相关性（P＜0.05）.结论 新疆哈萨克族MS及PAD的患病率均较高,且随着年龄增高而增高;PAD的患病率在MS人群中较非MS人群明显升高.PAD合并MS的危险因素为性别（男性）、年龄、收缩压、舒张压及血糖.Objective To investigate prevalence and risk factors of peripheral artery disease （PAD）, metabolic syndrome （MS） and peripheral artery disease complicated with metabolic syndrome among Kazakh adults lived in Xinjiang Yili prefecture. Methods Four-stage cluster sampling method was used to select adults aged 35 years and over for the study from six cities and prefectures of Xinjiang. All the participants were interviewed with questionnaire to collect their demographic characteristics. Physical checksup and blood biochemical measurements were performed for all of them, as well as blood pressure was measured in their lower legs and arms to calculate ankle brachial pressure index （ ABPI）, a ratio of the blood pressure in the lower legs to that in the arms. Only data of Kazakh adults in Yili prefecture were analyzed in this paper, including prevalence and risk factors for PAD and MS, as well as their relationship.The patients with PAD were divided into two groups, one complicated with MS and the other without it Logistic regression analysis was used to identify potential risk factors for PAD and MS and their combination.Results A total of 1365 adult Kazakh people were surveyed. Prevalence of MS was 23.7 percent, 30.4 percent for men and 19.0 percent for women, respectively, and that of PAD was 9. 4 percent, 7.0 percent for men and 11.0 percent for women, respectively. Mean age in patients of PAD complicated with MS was older than that in those without MS （t=-5.348, P〈0.01）. Risk of PAD complicated with MS in Kazakh people associated with gender （ men）, age, systolic pressure, diastolic pressure and blood glucose level.（P〈0.05）. Conclusions Both prevalence of PAD and MS are significantly higher among Kazakh people in Yili prefecture of Xinjiang, and increase with age. Prevalence of PAD is significantly higher in those with MS than that in those without MS. Risk factors of PAD complicated with MS include gender（men）, age,systolic pressure, diastolic pressure and blood glucose level.

关 键 词：外周血管疾病 代谢综合征X 数据收集 

分 类 号：R589[医药卫生—内分泌]