2型糖尿病患者颈动脉粥样硬化与总胆红素的关系  

Relationship between total serum bilirubin and carotid atherosclerosis in type 2 diabetes mellitus

作　　者：徐曜[1] 刘涛[1] 明洁[1] 王尧[1] 翟文松[1] 姬秋和[1] 

机构地区：[1]解放军第四军医大学西京医院内分泌代谢科,西安710032

出　　处：《中华全科医师杂志》2011年第3期209-211,共3页Chinese Journal of General Practitioners

摘　　要：对548例2型糖尿病患者行颈动脉超声检查,比较分析有、无颈动脉粥样硬化患者的血糖、糖化血红蛋白、胆红素、血脂等指标差异.有、无动脉粥样硬化患者的血清胆红素水平分别为（13.0±7.1）和（10.9±4.9）μmol/L,两者之间差异有统计学意义（P＜0.01）;logistic回归分析显示总胆红素水平与颈动脉粥样硬化呈负相关（P＜0.05）.提示高血清胆红素可能对2型糖尿病大血管病变具有保护作用.Ultrasonography examinations were performed for carotid atherosclerosis in 548 patients with type 2 diabetes mellitus （T2DM）. Blood glucose, glycosylated hemoglobin, total serum bilirubin, uric acid, total cholesterol （ TC ）, triglycerides （ TG）, high-density lipoprotein （HDL）, low-density lipoprotein （LDL） were measured. Total serum bilirubin level in T2DM patients without carotid atherosclerosis was （13.0±7. 1 ）μmol/L, while that was （10. 9 ± 4. 9 ）μmol/L in patients with carotid atherosclerosis （P 〈0. 01 ）. The logistic analysis showed that total serum bilirubin level was negatively related to the presence of carotid atherosclerosis （ P 〈 0. 05 ）, which indicated that higher level of total serum bilirubin might be a protective factor for macroangiopathy in T2DM.

关 键 词：糖尿病 2型 颈动脉疾病 

分 类 号：R587.1[医药卫生—内分泌]