聚(乳酸-氨基酸)共聚物的合成研究进展  

Progress in Research on the Synthesis of Poly(lactic acid-co-amino acid) Copolymers

作　　者：张晓飞[1] 魏兴[1] 王香梅[1] 

机构地区：[1]中北大学化工与环境学院,山西太原030051

出　　处：《化学与粘合》2011年第2期53-55,共3页Chemistry and Adhesion

摘　　要：吗啉-2,5-二酮及其衍生物的开环聚合作为合成聚(乳酸-氨基酸)共聚物的主要方法,由于其单体繁琐的合成过程,较低的产率,使得合成共聚物的成本过高,极大限制了其在医药领域的广泛应用,为此,研究人员已经开始探索新的合成方法。对近几年来氨基酸与丙交酯的共聚和氨基酸与乳酸的直接熔融聚合的研究情况进行介绍。The ring-opening polymerization of morpholine-2,5-dione and its derivatives is the main method to produce the poly（lactic acid-coamino acid ）（PLAA）. The complex synthesis of monomers and low yield causes high cost of synthetic eopolymers, it limits a wide application in medicine to a large extent. Therefore the researchers have been exploring the new synthetic methods. The recent progresses in study on the copolymer- ization of amino acid and lactide and the direct melt polymerization of amino acid and lactic acid are introduced.

关 键 词：吗啉-2 5-二酮及其衍生物 聚(乳酸-氨基酸)共聚物 共聚 直接熔融聚合 

分 类 号：TQ322.97[化学工程—合成树脂塑料工业]