2型糖尿病对左室功能的影响  

Effect of type 2 diabetes mellitus on left ventricular function

作　　者：李论[1] 顾晔[1] 刘涛[1] 成忠[1] 胡立群[1] 高波[1] 

机构地区：[1]华中科技大学同济医学院附属普爱医院心内科,武汉430030

出　　处：《临床心血管病杂志》2011年第2期144-146,共3页Journal of Clinical Cardiology

摘　　要：目的:探讨2型糖尿病(DM)对心脏左室功能的影响。方法:选取行冠状动脉造影及左室造影中冠状动脉造影阴性患者193例作为研究对象,按是否患2型DM分为DM组(93例)和对照组(100例)。对比2组左室造影所测左室射血分数(LVEF)、左室舒张末容积指数(LVEDVI)、左室舒张末压(LVEDP)及心脏彩超测得心脏各参数间的差异,并进行统计学分析。结果:2组间LVEF、LVEDVI、左室直径、右房直径、右室直径差异无统计学意义(P>0.05),而DM组LVEDP高于对照组[(9.4±2.6)∶(7.9±2.0)mmHg(1 mmHg=0.133kPa)],P<0.01;DM组左房直径较对照组增大[(37.1±6.3)∶(34.6±0.6)mm],P<0.01;E/A比值较对照组降低(1.0±0.3∶1.1±0.3),P<0.05。结论:2型DM可降低患者的左室舒张功能。Objective：To explore the effect of type 2 diabetes mellitus（DM） on left ventricular function.Method：The total of 193 patients with negative coronary angiography between 2007-2009 in our hospital were selected,according to the state of glucose metabolism,they were divided into two groups： DM group,93 cases;CG（control group）,100 cases of non-diabetic patients.LVEF（left ventricular ejection fraction）,LVEDVI（left ventricular end-diastolic volume index）,LVEDP（left ventricular end diastolic pressure） measured by left ventricular angiography and some parameters measured by cardiac ultrasonography were compared between the two groups.Result：There were no significant difference of LVEF,LVEDVI,LV,RA,RV between the two groups（P0.05）,while the LVEDP much higher in DM group than CG group,reaching statistical significance（9.4±2.6） vs（7.9±2.0）,P0.001;and according the.cardiac ultrasonography,LA is larger（37.1±6.3） vs（34.6±0.6）mm,P=0.004）,E/A ratio is lower（1.0±0.3） vs（1.1±0.3）,P=0.034 in DM group.Conclusion：Patients with type 2 DM can reduce the left ventricular diastolic function.

关 键 词：糖尿病 左室造影 左室射血分数 左室舒张末容积指数 左室舒张末压 

分 类 号：R587.1[医药卫生—内分泌]