HIV／AIDS患者眼部带状疱疹感染观察  

Clinical observation of herpes zoster virus infection in the eye area of HIV/AIDS patient

作　　者：朱翠萍[1] 

机构地区：[1]郑州市第六人民医院眼科,郑州河南450005

出　　处：《中国实用眼科杂志》2011年第2期177-178,共2页Chinese Journal of Practical Ophthalmology

摘　　要：目的探讨HIV／AIDS患者眼部带状疱疹感染的病变特点、临床症状、治疗及预后。方法回顾性分析205例（294只眼）HIV／AIDS患者的临床资料，包括视力、眼前节、眼底检查及外周血CD4^＋T淋巴细胞数，其中26例（26只眼）眼部带状疱疹感染患者早期给予更昔洛韦眼用凝胶点眼等药物治疗。结果HIV／AIDS患者CD4cr淋巴细胞数多于200个／mms者，带状疱疹感染临床症状相对较轻，眼部并发症少，病程短，约2-4周，愈合后视力无影响；CD4^＋T淋巴细胞数少于200个／mm^3的AIDS患者，临床症状较重，眼部并发症较多，病程较长，约3。5周，神经痛可持续半年以上，视力无影响或不同程度的下降，2例用药不及时或使用疗效欠佳药物的患者，出现严重的眼部并发症，视力损害严重。结论HIV／AIDS患者眼部带状疱疹感染，重在早期诊断，早期高效药物治疗。Objective To investigate the manifestations, treatment and prognosis that herpes zoster in the eye area of HIV/AIDS patients. Methods Two hundred and five patients were recruited. Two hundred and ninety-four eyes underwent ophthalmologic examination that included vision acuity, anterior segment, fundus examination and the amount of the CD4^＋ T-lymphocyte. Ganciclovir ophthalmic gel and other medical treatment were adoptted to 26 herpes zoster virus patient. Results The HIV/AIDS patients whose CD4^＋ T-lym- phocyte was more than 200/mm^3, the manifestations of the herpes zoster virus was not very serious, complications was less, the course of disease lasted shorter （about 2-4 weeks）, and there wouldn＇t be much influence in the vision acuity after recovery. While, the HIV/AIDS patients whose CD4^＋ T-lymphocyte was less than 200/mm^3, the manifestations of the herpes zoster virus was more serious, complications was more, the course of disease lasted longer （about 3-5 weeks）, the neuralgia could last more than half a year, and the vision acuity could be all the same as before or become worse in some degree. Two patients who didn＇t get medicine in time or the effect of medicine was not good enough, eventually got serious complication and the vision acuity became severe impaired. Conclusions The treatment in early stage and the efficient medicine really count a lot for the treatment of HIV/AIDS patient with herpes zoster virus.

关 键 词：HIV/AIDS 带状疱疹 更昔洛韦 

分 类 号：R512.91[医药卫生—内科学]