257例颅脑损伤患者合并肺部感染的特点及治疗  

Characteristics of 257 cases of craniocerebral injury patients combined with pulmonary infection and its treatment

作　　者：王浩[1] 吕建华[1] 田力学[1] 

机构地区：[1]北京市通州区潞河医院神经外科,北京101149

出　　处：《中华医院感染学杂志》2011年第6期1118-1120,共3页Chinese Journal of Nosocomiology

摘　　要：目的观察颅脑损伤患者合并肺部感染病原菌特点及耐药性情况。方法回顾性分析257例颅脑损伤患者合并肺部感染的临床资料。结果共分离出257株病原菌,革兰阴性菌199株,占77.43%,革兰阳性菌51株,占19.84%,真菌7株,占2.73%;以肺炎克雷伯菌、铜绿假单胞菌、金黄色葡萄球菌和大肠埃希菌为主,分别占25.29%、15.95%、15.56%和14.79%;病原菌呈现出较高的耐药性。结论颅脑损伤患者合并肺部感染以革兰阴性菌为主,耐药性高,应引起临床重视。OBJECTIVE To investigate the characteristics of pathogens causing pulmonary infection in patients with craniocerebral injury and the drug resistance.METHODS The clinical data of 257 patients with pulmonary infection in patients with craniocerebral injury were retrospectively analyzed.RESULTS A total of 257 strains of pathogens were isolated,and the Gram-positive bacteria（51 strains）,Gram-negative bacteria（199 strains）,and fungi（7 strains） took proportions of 19.84%,77.43% and 2.73%,respectively.The main pathogens were Klebsiella pneumoniae,Pseudomonas aeruginosa,Staphylococcus aureus,and Escherichia coli,accounting for 25.29%,15.95%,15.56% and 14.79%,respectively.The pathogens showed high drug resistance.CONCLUSION Gram-negative bacteria are the main pathogens that cause pulmonary infection in patients with craniocerebral injury and show high drug resistance which should be paid more attention.

关 键 词：颅脑损伤 肺部感染 病原菌 耐药性 

分 类 号：R181.32[医药卫生—流行病学]