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作 者:施颖辉[1] 李文生[1] 陈华蓉[1] 王爱晓[1]
机构地区:[1]温州医学院附属眼视光医院感染管理科,浙江温州325027
出 处:《中华医院感染学杂志》2011年第6期1200-1202,共3页Chinese Journal of Nosocomiology
摘 要:目的通过综合干预促进抗菌药物的临床合理应用。方法分别抽取2006年10月、2009年10月出院病例,比较和分析抗菌药物使用情况。结果抗菌药物使用率、手术期预防使用率、手术后期用药率均降低,2006、2009年组分别为40.13%与24.57%、41.71%与25.97%、99.43%与82.04%,差异有统计学意义;手术期用药率升高,2006、2009年组分别为46.59%与65.27%,差异有统计学意义;两组联合用药(均<10.00%)、使用率最高的抗菌药物(均为头孢一、二代)比较变化不大。结论依据《抗菌药物临床应用指导原则》加强管理行之有效,但仍有不足之处需加强管理。OBJECTIVE To enhance the rational usage of antibiotics by comprehensive interventional measures in clinics.METHODS The antibiotics usage status among discharged cases in Oct 2006 and cases in Oct 2009 were compared and analyzed.RESULTS Compared with 2006 group,the use rate of antibiotic medication in 2009 were decreased(40.13% and 24.57%,P〈0.001).The percentage of perioperative prophylaxis antibiotics were decreased(41.71% and 25.97%,P〈0.001).The percentage of postoperative antibiotics were decreased(99.43% and 82.04%,P〈0.001).The percentage of intraoperative antibiotics were higher(46.59% and 65.27%).The combination and the drugs in the first row of two groups changed little.CONCLUSION The administration of antibiotics usage has been proved effective based on guidelines for clinical application of antibiotics,but there are some problems needed to further management.
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