米非司酮配伍米索前列醇用于绝经后妇女取IUD 60例疗效观察  

Simultaneous administration of Mifepristone and Misoprostol for removal of intrauterine device in 60 cases menopausal women

作　　者：商凤云[1] 康丽红[1] 

机构地区：[1]河北省秦皇岛市第二医院妇科,河北秦皇岛066600

出　　处：《中国医药导报》2011年第8期71-72,共2页China Medical Herald

摘　　要：目的:观察米非司酮配伍米索前列醇在绝经后妇女取IUD的临床效果。方法:选择门诊要求取IUD的绝经妇女120例,随机分为两组。观察组60例,术前给予米非司酮25 mg口服,每日1次,连续3 d,第4天术前2 h舌下含服米索前列醇400μg。服药前后2 h空腹。对照组60例,不使用任何药物直接取IUD。结果:观察组60例取器手术全部成功,成功率为100%(60/60),对照组成功率为80%(48/60)。结论:米非司酮和米索前列醇用于绝经后妇女取IUD,可以提高取器成功率,值得临床推广应用。Objective： To study simultaneous administration of Mifepristone and Misoprostol for removal of intrauterine device （IUD） in the menopausal woman. Methods： From September 2008 to March 2010, 120 cases menopausal women who required to remove the IUD were randomly divided into observation group （n= 60） and control group （n=60）. Prior to removal of IUD, the women in observation group were given Mifepristone at a dose of 25 mg, once daily for 3 days, following by administration of Misoprostol at a dose of preoperative 2 h sublingual 400 μg at the fourth day. In control group, the women were given no medicine before IUD removal. A success on the first attempt at IUD removal with additional management was considered successful procedure. Results： The IUD was successfully removed in all women of observation group with the success rate of 100%. In control group, the IUD was successfully removed in 48 of 60 women with the success rate of 80%. Conclusion： Simultaneous administration of Mifepristone and Misoprostol can be helpful for the IUD removal procedure in the menopausal woman.

关 键 词：米非司酮 米索前列醇 IUD 绝经后妇女 

分 类 号：R715.2[医药卫生—妇产科学]