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作 者:黄文湧[1] 王艳[1] 杨敬源[1] 杨星[1] 汪俊华[1] 邓厚才[1] 韩志琰[1]
机构地区:[1]贵阳医学院公共卫生学院流行病学教研室,贵阳550004
出 处:《现代预防医学》2011年第6期1001-1003,1006,共4页Modern Preventive Medicine
基 金:贵州省省长资金(黔科教办(2004)07);贵州省教育厅自然科学研究项目(黔教科2005108)
摘 要:[目的]探讨社会支持对阿尔茨海默病(AD)发生的影响,为进一步探明AD的病因和制订预防策略奠定基础。[方法]采用以社区人群为基础的成组病例对照研究,对可能影响AD发生的社会支持相关因素进行分析。资料分析采用非条件Logistic回归分析方法,先进行单因素分析,然后再进行多因素分析。[结果]在控制了年龄和受教育程度后,与配偶和子女共同居住的老年人患AD的危险性最低(OR=0.14,95%CI:0.03~0.67),其次是丧偶与子女居住的老年人(OR=0.30,95%CI:0.12~0.79),与配偶居住的老年人(OR=0.35,95%CI:0.14~0.85);家人尊重和有子女者可能是AD的保护性因素(OR=0.40,95%CI:0.17~0.95;OR=0.17,95%CI:0.03~0.89);独自在家的频率≥2次/周者患AD的危险性明显增多(OR=2.37,95%CI:1.10~5.09)。[结论]AD的发生和发展与老年人的社会支持状况有关。调动有效的社会支持来源,尽可能地让老年人获得帮助与支持,有助于预防AD的发生。[Objective] To investigate the relationship between social support and Alzheimer's disease (AD) among the elderly in community of Guiyang. [ Methods ] By using a case-control study based on apopuladon in community, the effect of social support on AD was analyzed. A non-conditional logistic regression was used in data'analysis. [ Results] After adjusting for age and education, it was showed that the lowest risk of AD was existed in the elderly living with their partners and their children (OR=0.14, 95%CI: 0.03-0.67), and then the widow hving with their children, and with their partners (OR= 0.30, 95%CI: 0.12-0.79; 0R=0.35. 95%CI: 0.14-0.85). Respect perceived from the family members and having children might have protective effects on AD (OR=0.40, 95%CI: 0.17-0.95; 0R=0.17, 95% CI: 0.03-0.89). The elderly who hved alone over 2 times per week showed a higher risk for AD (0R=2.37, 95%CI=1.10-5.09). [Conclusion] Social support plays an important role in the development of AD. It will be helpful to prevention of AD through providing effective social support for the elderly.
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