环糊精衍生物的点击化学合成法的研究进展  

Progress on Cyclodextrin Derivatives Synthesized via "Click" Chemistry

作　　者：安伟[1] 张华承[1] 孙涛[1] 李祥军[1] 郝爱友[1] 

机构地区：[1]山东大学化学与化工学院,济南250100

出　　处：《有机化学》2011年第3期275-285,共11页Chinese Journal of Organic Chemistry

摘　　要：点击化学("click"chemistry)具有反应条件温和、选择性高、产率高、纯化步骤简单等优点,现已成为当前的一大研究热点.环糊精具有"内疏水、外亲水"的锥筒状空腔结构,是超分子化学的重要主体之一,合成功能各异的环糊精衍生物引起了人们的广泛关注.综述了点击反应合成环糊精衍生物的最新研究进展及其应用,并对其发展前景做了展望.＂Click＂ chemistry has become a hot issue in present because of their mild reaction conditions,high selectivity,high yields and simple purification steps.Cyclodextrin and their derivatives（CDs） having skirt-shaped cyclic oligosaccharides with a hydrophobic inner cavity and a hydrophilic outside surface are important hosts of supramolecular chemistry.Synthesizing CDs with various properties has gained much at-tention.In this paper,CDs synthesized via ＂click＂ reaction and their applications are reviewed.Based on these reviews,the prospect is discussed.

关 键 词：点击化学 环糊精 有机合成 超分子化学 应用 

分 类 号：O636.12[理学—高分子化学]