不同程度阻塞性睡眠呼吸暂停综合征患者的心理状况及睡眠结构分析  

Analysis on the psychological status and sleep structure of patients with obstructive sleep apnea syndrome at different degrees

作　　者：单希征[1] 高云[1] 马丽涛[1] 吕明[1] 李红云[1] 张丽萍[1] 杨金丽[1] 

机构地区：[1]中国人民武装警察部队总医院耳鼻咽喉科,北京100039

出　　处：《中国中西医结合耳鼻咽喉科杂志》2011年第1期15-18,共4页Chinese Journal of Otorhinolaryngology in Integrative Medicine

基　　金：中国人民武装警察部队总医院重点课题(项目编号wz200507)

摘　　要：目的分析不同程度阻塞性睡眠呼吸暂停综合征(OSAS)患者的心理健康状况及睡眠结构特点。方法 54例经多导睡眠监测诊断的OSAS患者,依据呼吸暂停低通气指数(AIII)分度,并通过其睡眠结构特点分析和症状自评量表(SCL-90)评估,探讨其间的相关性。结果本组患者症状自评量表躯体化、强迫、人际敏感、焦虑、敌意和精神病性因子分较国内常模明显增高(P<0.05),呼吸暂停低通气指数能够显著正向预测躯体化、强迫、人际敏感、抑郁、精神病性及量表整体症状。中重度组患者的非快速眼动睡眠(NREM)Ⅰ期所占比例明显增加(P<0.05),而快速眼动睡眠期(REM)所占比例则明显少(P<0.05)。结论 OSAS患者存在睡眠结构紊乱及心理健康卫生问题,其严重程度与OSAS病情程度密切相关。Objective To investigate the psychological status and sleep structure of patients with obstructive sleep apnea hypopnea syndrome （OSAHS） at different degrees. Methods Fifty-four patients with OSAHS, diagnosed based on the diagnostic criteria of polysomnogram （PSG）, were classified into different severe degrees on the basis of apnea-hypopnea index （AHI） at first. Then, they were assessed with the analysis of sleep structure and the evaluation of SCL-90 to explore the possible association of these assessment results with the degree of lesion. Results The scores of somatization, constraint, interpersonal sensitivity, depression, anxiety and psychoticism, as evaluated by SCL-90 among these cases of OSAHS, were significantly higher than that evaluated by other measuring scales noremally used in China （P〈0.05）. Here, it was shown that the indicator of AHI could positively predicit the changing tendency of symptoms scored by SCL-90 as mewntioned as above. Furthermore,compared with mild OSAHS group, the cases at moderate and severe degrees of severity showed an increased percentage of NREM and reduced percentage of REM during stage I of sleeping （P〈0.05）. Conclusion Patients with OSAHS have disordered sleep structure and may show obvious mental problems. The severity of these problems is significantly associated with the severe degree of the lesion as indicated by AHI.

关 键 词：阻塞性睡眠呼吸暂停综合征 睡眠结构紊乱 抑郁 焦虑 心理健康 

分 类 号：R766[医药卫生—耳鼻咽喉科]