妊娠哺乳相关骨质疏松症  

Osteoporosis associated pregnancy and lactation

作　　者：苏宏业[1] 黄媛[1] 李圣琦[1] 黄炫赓[1] 

机构地区：[1]广西医科大学第一附属医院代谢糖尿病中心,南宁530007

出　　处：《中国骨质疏松杂志》2011年第2期150-152,共3页Chinese Journal of Osteoporosis

摘　　要：目的提高对妊娠哺乳相关骨质疏松症(PLO)的认识。方法回顾分析2例PLO的临床资料,同时对相关文献进行复习。结果 2例PLO患者均表现为妊娠晚期腰背痛,产后加重,活动受限,胸腰椎多椎体骨折,腰椎和骨盆骨质疏松。停止哺乳并予钙剂、活性维生素D和双膦酸盐治疗后随访发现,腰背痛等症状在治疗后半年至9个月消失,无新发骨折,骨密度增加。结论在妊娠晚期或产后出现的腰背痛应考虑PLO。钙剂、活性维生素D的补充及抗骨吸收治疗对PLO可能有效。Objective To understand more about pregnancy and lactation-associated osteoporosis （PLO）. Methods Clinical information of 2 patients with PLO was analyzed. We also reviewed the related references in the literature. Results Both patients showed symptoms of back pain in late pregnancy period. The pain increased after labouring and caused limited mobility. Muhiple fractures of thoracic and spinal vertebra and vertebral and pelvic bone loss occurred. Lactation was terminated after diagnosis and both patients received treatment of calcium, activated vitamin D, and biphosphonates. The back pain disappeared during a 6-9 month follow-up. No new fractures occurred and bone mineral density increased. Conclusion PLO should be considered when back pain presented in patients during late pregnancy or after laboring. Supplements of calcium and activated vitamin D and anti-resorption treatment could be effective.

关 键 词：骨质疏松 妊娠 哺乳 

分 类 号：R681[医药卫生—骨科学]