相对造影参数在乳腺肿物良恶性鉴别诊断中的价值  

The value of relative CEUS parameters in the differential diagnosis between benign and malignant breast lesions

作　　者：刘晓芳[1] 毛世杰[1] 康春松[1] 

机构地区：[1]山西医科大学第一医院,山西太原030001

出　　处：《实用医学影像杂志》2011年第1期56-58,共3页Journal of Practical Medical Imaging

摘　　要：目的利用超声造影技术,探讨相对造影参数在乳腺病灶良恶性鉴别诊断中的价值。方法选用造影剂SonoVue,对34例乳腺病灶进行超声造影(良性14例,恶性20例),应用随机配置的Qontraxt定量分析软件,对病灶及病灶旁组织勾勒感兴趣区,测量其声学定量参数,进一步获得相对造影参数。结果病灶的相对峰值强度、相对达峰时间、相对曲线下面积,良恶性病灶之间差异均具有统计学意义(P<0.05)。病灶的相对曲线尖度,良恶性病灶之间差异无统计学意义(P>0.05)。结论乳腺良恶性病灶的超声造影灌注模式各有特点。超声造影研究中,应充分重视病灶周围腺体的增强情况,病灶的相对造影参数有助于良恶性的鉴别诊断。Objective To evaluate the significance of parameters and relative parameters of contrast-enhanced ultrasound（CEUS） in the differential diagnosis between benign and malignant breast lesions.Methods A total of 34 patients with breast lesions（14 benign,20 malignant） were examined by CEUS after injection of the contrast agent SonoVue.The intensity and the perfusion characteristics of breast lesions were analyzed.The ROI（region of interest） of lesions and surrounding tissues were drawn by software of Qontraxt,then the parameters and calculation of the relative parameters of CEUS were obtained.Pathology was used as the golden diagnostic criteria.Results The lesions＇ relative TP（time to peak）,PI（peak intensity） and AUC（area under the curve） were different between benign and malignant lesions （P0.05）,but no significant difference was detected in relative sharpness between benign and malignant lesions（P0.05）.Conclusion The perfusion characteristics were different between the benign and malignant lesions（P0.05）.More attention should be paid to enhancement of surrounding tissues in the study of CEUS.The relative parameters of CEUS are useful to differentiate benign from malignant breast lesions.

关 键 词：乳腺病灶 超声造影 灌注模式 相对造影参数 

分 类 号：R445.1[医药卫生—影像医学与核医学] R737.9[医药卫生—诊断学]