以脊柱侧弯、高血压为表现大动脉炎1例并文献复习  

Takayasu＇ s arteritis manifesting as scoliosis and hypertention： a case report and review of literatures

作　　者：余金泉[1] 李进[2] 肖海鹏[1] 

机构地区：[1]广州市中山大学附属第一医院内分泌科,510080 [2]广州市中山大学附属第一医院特诊医疗中心,510080

出　　处：《国际医药卫生导报》2011年第5期566-568,共3页International Medicine and Health Guidance News

摘　　要：目的探讨大动脉炎（TA）的临床特点、诊断及治疗，以提高对该病的认识。方法报告1例我院确诊以脊柱侧弯、高血压为表现的TA患者并结合文献复习。结果TA是一种病因不明的慢性肉芽肿性动脉炎，好发于青年女性及儿童，主要临床表现为仝身炎性反应以及受累脏器缺血症状。TA临床表现不典型，急性炎性期多缺乏特异性表现。就诊时多处于疾病晚期（脏器缺血期），治疗效果不满意。结论对于多系统、多脏器损害的患者，应全面检查，尤其是注重检查四肢血压、脉搏及血管杂音，早期进行血管彩超、CT等影像学检查可提高早期诊断率。对所有患者均需要进行影像学检查以及大血管造影了解动脉受累情况，据受累血管的部位、程度和范同不同，选择合适的治疗方案。Objective To investigate the clinical characteristics, diagnosis, and treatment of Takayasu＇ s arteritis （TA） for further understanding of this disease. Methods We reported a case of TA manifesting as scoliosis and hypertention and reviewed the related lileratures. Results TA, commonly seen in young females and children, is a chronic agranulonlatous arteritis of unknown cause, manifesting mainly as systemic inflammatory responses and ischemic signs of the involved organs. The diagnosis of TA is often delayed because of lack of specific clinical features at the acute inflammatory period and the efficacy is usually unsatisfactory due to the occurrence of organic ischaemia. Conclusions In order to rule out TA, patients with multi-systemic and muhi-viscera lesions should have comprehensive examination, especially tot those with hypertension, pulseless, and vascular bruits. Early uhrasonography and computed tomography can enhanee the early diagnostic rate. Imaging studies, as well as anglography are needed to look into the conditions of involved arteries. Proper treatment should be administered according to the location, degree, and size of the involved arteries.

关 键 词：大动脉炎 脊柱侧弯 高血压 

分 类 号：R544[医药卫生—心血管疾病]