依帕司他与甲钴胺联合治疗糖尿病周围性神经性病变的疗效观察  

Clinical effect observation of combined treatment of epalresta and methycobal on diabetic peripheral neuropathy(PDN)

作　　者：李宝传[1] 刘珠英[1] 

机构地区：[1]广州中山大学附属第三医院药剂科,510630

出　　处：《内蒙古中医药》2011年第4期89-89,共1页Inner Mongolia Journal of Traditional Chinese Medicine

摘　　要：目的:探讨依帕司他与甲钴胺联合治疗糖尿病周围性神经性病变的临床疗效。方法:将90例糖尿病周围性神经性病变的患者随机分成两组,分别为治疗组和对照组,治疗组采用依帕司他与甲钴胺联合治疗;对照组单用甲钴胺治疗。疗程均为4周,以观察治疗的有效率。结果:治疗组总有效率为93.33%,对照组总有效率为64.44%,明显优于对照组(P<0.05)。结论:依帕司他与甲钴胺联合治疗可明显改善糖尿病周围性神经性病变的治疗效果。依帕司他与甲钴胺联合治疗糖尿病周围性神经性病变的疗效优于单药治疗组。OBJECTIVE To study the clinical effect of combined treatment of epalresta and methyeobal on diabetic peripheral neuropathy. METHODS Ninety patients with diabertic peripheral neuropty（DPN） were randomly divided into the control group which was treated with methycobal and the treatment group which was treated with epalresta and methycobal. The courses of two groups are both in 4 weeks. Observe the effective rate of treament. RESULTS The total efficient of treatment group is 93.33% while 64.44% of control group.It is obvious that treatment group is more effeeitve than control group （P〈0.05）. CONCLUSION It can be obviously impoved the clinical effect of diabetic peripheral neuropathy by combining treatment of epalresta and methycobal.The treatment effect is superior to single drug therapy groups.

关 键 词：依帕司他 甲钴胺 糖尿病周围性神经性病变 

分 类 号：R587.2[医药卫生—内分泌]