连云港公务员体检人群血尿酸水平的临床分析  

Clinical Analysis of Hyperuricemia in Civil Servants from the City of Lianyungang City

作　　者：刘清[1] 王小萍[1] 卢长芳[1] 洪红[1] 王云慧[1] 陈英文[1] LIU Qing,WANG Xiao-ping,LU Chang-fang,et al （The centre of physical examination, the No.2 Peoplels Hospital, Lianyungang 222006,China）

机构地区：[1]连云港市第二人民医院体检中心,江苏连云港222006

出　　处：《医学信息》2011年第5期1208-1210,共3页Journal of Medical Information

摘　　要：目的分析连云港市公务员体检人群的血尿酸水平与特点。方法对7765例公务员，按年龄、性别分组分析高尿酸血症的患病率；并对高尿酸血症组与非高尿酸血症组0脑血管病的危险因素进行比较。结果：高尿酸血症的患病率男性为15．29％，女性为4．81％；随着年龄增长高尿酸血症的患病率也增加；不同性别同一年龄组比较。高尿酸血症的患病率男性高于女性（P〈0．0001），而≥65岁年龄组，男女之间高尿酸血症的患病率无统计学差异（P〉0．05）高尿酸血症组与非高尿酸血症组之间比较；高血压病、空腹血糖升高、总胆固醇（TC）升高、超重／肥胖的及颈动脉斑块的发生率均是前者高于后者，并有统计学差异（P〈0．05—0．005）；而甘油三酯（TG）水平升高组之间无统计学差异（P〉0．05）。结论高尿酸血症的患病率在公务员人群中是比较突出：而高尿酸血症患者其心脑血管病危险因素的发生率也明显增高。Objective To analyse the level and characteristic of serum uric acid in civil servants from the city of Lianyungang. Methods We investigated the level of serum uric acid in 7765 civil servants grouped by gender and ages. And there is a comparison between the hyperurieemia group and the non-hyperuricemia one for the risk factors of cardiac-cerebral vascular disease. Results The prevalences of hyperuricemia were 15.29% and 4.81% for men and women, respectively. And we found a higher prevalence associated with age. In the 〈65 years old groups ,the prevalence of men is higher than that of women （P-value for trends〈0.0001）, while in the ≥65 years old group, there is no significant association with gender （P-value for trends 〉0.05）. The hyperuricemia group had a higher prevalence of the risk factors than the non-hyperuricemia group, including hypertension, impaired fasting glucose, drop of high density lipoprotein cholesterol, high level of total cholesterol, high level of low density lipoprotein cholesterol, overweight/obesity and carotid plaque. While for the high level of triglyceride, there is no statistical significance （P-value for trends 〉0.05）.Conclusion The prevalence of hyperuricemia in the civil servants of Lianyungang City was high in comparison with the average of the population in China. The incidence of the risk factors of cardiac-cerebral vascular disease was obviously increased in the civil servants with hyperuricemia.

关 键 词：高尿酸血症 年龄 性别 危险因素 

分 类 号：R587.1[医药卫生—内分泌;医药卫生—临床医学;医药卫生—内科学]