同源异型盒基因研究  

Study on Homeobox Gene

作　　者：任德全[1] 刘玉芬[1,2] 许丽敏[1] 高学军[2] 

机构地区：[1]哈尔滨师范大学生命科学与技术学院,黑龙江哈尔滨150025 [2]东北农业大学农业生物功能基因重点实验室,黑龙江哈尔滨150020

出　　处：《安徽农业科学》2011年第4期1949-1950,共2页Journal of Anhui Agricultural Sciences

基　　金：东北农业大学农业生物功能基因重点实验室基金项目(NXGJ2009-004)

摘　　要：同源异型盒基因家族(homeobox gene family)均含有一个高度保守的同源异型盒,用于编码转录调控因子(同源异型盒蛋白),在细胞的增殖分化中起着精密的调节作用。同源异型盒基因的突变不仅会导致发育畸形,而且还与某些肿瘤的发生发展密切相关。就同源异型盒基因的结构特点及其在肿瘤发生中的作用进行了综述。There was a highly conservative homeobox in nearly all homeobox gene family,which used for encoding transcription regulatory factors（homeobox protein） and generated the accurate regulating action in cells proliferation and differentiation.The mutation of homeobox gene not only resulted in development malformation,but also had a close relationship with the occurrence and development of some tumours.The structural features of homeobox gene and the effect in tumours were summarized.

关 键 词：同源异型盒基因 结构 功能 应用 

分 类 号：S188[农业科学—农业基础科学]