三种助孕技术治疗多囊卵巢综合征不孕的疗效比较  

The comparison of the results of three kinds of assisted reproductive technologies for the treatment of sterility patients with polycystic ovarian syndrome.

作　　者：李媛[1] 冯云[2] 陈子江[1] 

机构地区：[1]山东医科大学,25001 [2]山东省立医院生殖医学中心

出　　处：《现代妇产科进展》1999年第3期242-244,共3页Progress in Obstetrics and Gynecology

基　　金：山东省科委资助项目及卫生部青年科学基金

摘　　要：目的：观察３种助孕技术：ＩＶＦＥＴ、ＧＩＦＴ和控制性超促排卵（ＣＯＨ）后自行同房对多囊卵巢综合征（ＰＣＯＳ）不孕患者的疗效。方法：应用３种方法治疗，观察各组的临床妊娠率和发生卵巢过度刺激综合征（ＯＨＳＳ）的情况。结果：ＩＶＦＥＴ和ＧＩＦＴ与ＣＯＨ相比能得到更高的临床妊娠率，而前二者发生ＯＨＳＳ的危险性明显低于后者。结论：为避免ＣＯＨ后发生ＯＨＳＳ，建议对因ＰＣＯＳ不孕的患者采取体外助孕技术治疗。应用何种技术要根据患者的具体情况而定。如果有至少１ 条输卵管完全正常，可先试行ＧＩＦＴ。此外，须将多余的卵子进行体外授精试验，观察其受精及卵裂情况，从而对今后的治疗提出指导性建议，并要将得到的胚胎进行冷冻保存，以备今后使用。Objective:To compare the three assisted reproductive technologies(IVF ET,GIFT and COH)for the treatment of patients with PCOS.Methods:The above mentioned three methods were used to treat 3 groups of PCOS patients separately.The clinical pregnancy rates and the occurrence of OHSS in each group were observed.Results:IVF ET and GIFT could achieve higher success than COH for the treatment of PCOS,and the risk of OHSS was much lower than that in the later.Conclusions:Avoiding the risk of OHSS,IVF ET or GIFT is the favorable protocol to be chosen.If the patient has at least one absolutely normal fallopian tube,it's better to choose GIFT as the first line treatment method,and the excess oocytes should be ferformed invitro fertilization test.Thus,it will be a guidance to the treatment of that woman in the future,and the acquired embryo ought to be preserved by freeze for future application.

关 键 词：多囊卵巢综合征 胚胎移植 配子移植 女性不育 

分 类 号：R711.605[医药卫生—妇产科学] R711.750.5[医药卫生—临床医学]