代谢综合征引起血栓性疾病的研究进展  

Research Progress in Thrombotic Diseases Caused by Metabolic Syndrome

作　　者：王喜红[1] 金红[2] 

机构地区：[1]汕头大学医学院,广东汕头515041 [2]汕头大学医学院第一附属医院心内科,广东汕头515041

出　　处：《医学综述》2011年第5期767-769,共3页Medical Recapitulate

基　　金：广东省自然科学基金(8151503102000006)

摘　　要：代谢综合征是一种以多种心血管疾病危险因素集聚为特征的临床综合征。其引起血栓性疾病的机制尚未完全阐明。近年来的研究认为,代谢综合征患者易患血栓性疾病是多种因素相互作用的结果。其中,内皮功能损伤、血小板高反应性、慢性炎症及凝血纤溶失衡在代谢综合征患者血栓性疾病的发病中起了重要作用。Metabolic syndrome is a cluster of risk factors for cardiovascular diseases.The pathogenesis of thrombosis caused by metabolic syndrome has not been fully clarified.Recent studies suggest that thrombosis is a complex interaction of various factors in metabolic syndrome patients.Endothelial dysfunction,platelet hyperreactivity,chronic inflammation,and imbalance of coagulation factors and proteins regulating fibrinolysis play a key role in the pathogenesis of thrombosis in metabolic syndrome patients.

关 键 词：代谢综合征 血栓性疾病 机制 

分 类 号：R589[医药卫生—内分泌]