糖尿病并发心肌梗死患者C反应蛋白和致动脉硬化指数分析及临床意义  

The Relationship between hs-CRP and Atherogenic Index of Plasma(AIP) in Patients with Diabetic Myocardical Infarction and It′s Significance

作　　者：韩爽[1] 沙子健[2] 齐晓丹[3] 曹德华[1] 于海涛[4] 

机构地区：[1]齐齐哈尔医学院第一附属医院检验科,161041 [2]齐齐哈尔医学院药学实验中心,161006 [3]齐齐哈尔医学院生化教研室,161006 [4]齐齐哈尔医学院科技处

出　　处：《医学研究杂志》2011年第2期52-54,共3页Journal of Medical Research

基　　金：黑龙江省自然科学基金青年科学基金资助项目(QC2009C89)

摘　　要：目的探讨糖尿病并发心肌梗死患者超敏C反应蛋白(hs-CRP)与致动脉硬化指数(AIP)相关性及其临床意义。方法选取52例糖尿病并发心肌梗死患者,检测各患者血浆hs-CRP、HbAlc、CHO、TG、HDL-C、LDL-C等水平,计算致动脉硬化指数;选取60例糖尿病无心肌梗死患者作为对照组。结果糖尿病并发心肌梗死患者血浆hs-CRP、AIP明显高于对照组,并且无论是糖尿病并发心肌梗死还是对照组,hs-CRP水平与AIP无相关性。结论 hs-CRP与心肌梗死的发生有密切关系,可能是独立于TG、HDL-C、LDL-C以外的糖尿病并发心肌梗死相关危险因素。AIP与糖尿病并发心肌梗死有关。Objective To analyze the relationship between hs-CRP and AIP in patients with diabetic myocardical infarction and its significance.Methods The levels of hs-CRP,HbAlc,CHO,TG,HDL-C,LDL-C were determined in 52 patients with diabetic myocardical infarction and 60 controls.Results The mean level of hs-CRP and AIP were significantly higher in patient with diabetic myocardial infarction（4.32±2.10;0.303±0.236）than those of controls（1.14±0.640;0.111±0.178）.The hs-CRP level was not related to AIP in two groups.Conclusion Our results suggest that elevated hs-CRP level may be an independent risk indicator except TG,HDL-C,LDL-C in diabetic myocardial infarction.AIP may be related to the diabetic myocardial infarction.

关 键 词：超敏C反应蛋白 糖尿病并发心肌梗死 致动脉硬化指数 

分 类 号：R473.5[医药卫生—护理学]