胃转流术对代谢综合征改善作用的研究进展  

Review on Remission of Metabolic Syndrome after Gastric Bypass

作　　者：戴露倢[1] 王瑜[1] 王烈[2] 黄盛[2] 

机构地区：[1]安徽医科大学第一临床医学院,安徽合肥230032 [2]南京军区福州总医院普通外科,福建福州350025

出　　处：《中国普外基础与临床杂志》2011年第2期216-219,共4页Chinese Journal of Bases and Clinics In General Surgery

基　　金：福建省重点科技计划项目(项目编号:2009Y0039);南京军区医药卫生科研重点专项(项目编号:09Z031)~~

摘　　要：目的探讨胃转流术(GBP)对代谢综合征(MS)的影响及其作用机理。方法通过复习文献,回顾分析GBP对糖脂代谢和血压变化的影响。结果 GBP术后数天内,70%以上MS患者血糖、血脂达正常水平,血压控制有明显改善,而体重减轻迟于血糖、血脂变化。饮食、胃肠激素、脂肪细胞因子、脂肪分布等因素的改变参与GBP对MS的改善作用。结论 GBP似乎对控制MS有原发的、独立的影响,而非继发于对肥胖症的治疗。Objective To explore the effect of gastric bypass（GBP） on metabolic syndrome（MS） and the related mechanisms.Methods The literatures addressed the effect of GBP on glucose metabolism and blood pressure were retrospectively analyzed.Results It showed that GBP achieved durable level of blood glucose,remission of dylipidemia and hypertension,however,which occurred before significant weight loss.The changes of many factors such as food intake,gastrointestinal hormones,adipocytokines,fat distribution might be involved in GBP to improve MS.Conclusion GBP seems to achieve the control of MS as a primary and independent effect,rather than secondary to the treatment of overweight.

关 键 词：代谢综合征 胃转流 胰岛素抵抗 糖尿病 

分 类 号：R656.61[医药卫生—外科学]