肝泡型棘球蚴病非手术治疗的疗效评价  

Non-surgical Treatment for Nonresectable Advanced Hepatic Alveolar Echinococcosis

作　　者：唐群科[1] 张瑛[1] 李永寿[1] 袁春萍[1] 张冬天[1] 

机构地区：[1]中国人民解放军第四医院外三科,西宁810007

出　　处：《中国寄生虫学与寄生虫病杂志》2011年第1期46-48,共3页Chinese Journal of Parasitology and Parasitic Diseases

摘　　要：目的探讨非手术治疗的晚期肝泡型棘球蚴病患者的治疗方法。方法对中国人民解放军第四医院2006-2009年收治的25例无法根治性切除的肝泡型棘球蚴病患者进行回顾性调查分析,了解其治疗方法和疗效。结果 25例肝泡型棘球蚴病患者中,男性18例,女性7例,平均年龄为41岁。其中单纯药物治疗[持续服用阿苯达唑15～20 mg/(kg.d)]12例,药物结合穿刺治疗11例,药物结合介入治疗2例。阿苯达唑治疗2周为一疗程,一般持续3个疗程。治疗后1～4年共有18人获随访。其中单纯药物治疗组有效2例,改善7例;药物结合穿刺治疗组有效2例,改善5例;药物结合介入治疗组2例均无效。结论持续服用阿苯达唑可作为非手术治疗肝泡型棘球蚴病患者的主要治疗方法。Objective To investigate the therapeutic methods of nonresectable advanced hepatic alveolar echino-coccosis.Methods A retrospective study was carried out to analyze 25 cases of nonresectable advanced hepatic alveolar echinococcosis in the Fourth Hospital of PLA from 2006 to 2009.Results There were 18 male and 7 female patients with a mean age of 41 years.Twelve cases were treated with albendazole alone.Eleven patients were treated with albendazole com-bined with percutaneous puncture.Two cases were treated with albendazole combined with other intervention.A course of albendazole administration lasted 2 weeks with a dose of 15-20 mg/（kg·d） for 3 course in general.Eighteen patients were followed up for 1-4 years.In albendazole group,2 cases were effective and 7 cases were symptom-improved.Five partients got improved and 2 cases showed effective in albendazole combined with percutaneous puncture group.Two cases of albendazole combined with intervention group showed no efficacy.Conclusions Long-term use of albendazole is the main treatment for nonresectable advanced hepatic alveolar echinococcosis.

关 键 词：肝泡型棘球蚴病 非手术 治疗 

分 类 号：R383.33[医药卫生—医学寄生虫学]