乌梅散水提取工艺的正交试验研究  

Water Extraction Process of Wumei Powder by Orthogonal Design

作　　者：王智云[1] 赵琳琳[2] 吴金环[2] 赵媛[2] 肖倩[2] 韩刚[2] 

机构地区：[1]唐山市人民医院药剂科,河北唐山063000 [2]河北联合大学药学院,河北唐山063000

出　　处：《中药新药与临床药理》2011年第2期209-211,共3页Traditional Chinese Drug Research and Clinical Pharmacology

基　　金：国际合作项目:筛选治疗2型糖尿病中药复方有效成分及有效单体最佳配伍的实验研究(2008DFA31050)

摘　　要：目的优选水提取乌梅散中有效成分的最佳工艺。方法采用四因素三水平正交设计,高效液相色谱法测定乌梅散中梓醇含量,以提取物中梓醇含量为评价指标优化乌梅散的提取条件。结果乌梅散的最佳水提取工艺为加6倍量水煎煮1.5h,提取两次。结论乌梅散水提取工艺简单、易于操作、不使用有机溶剂、成本低廉。Objective To optimize the water extraction process of catalpol,one of the effective components of Wumei Powder.Methods L9（34） orthogonal experiment was adopted in this study.And the content of catalpol was determined and then used for the optimization of extraction conditions.Results The best extracting technical conditions were as follows： adding 6-fold water,extracting for 1.5 hour and extracting twice.Conclusion The optimized extraction process of Wumei Powder is simple and feasible,with less cost.

关 键 词：乌梅散 正交试验 地黄 梓醇 HPLC 

分 类 号：R284[医药卫生—中药学] TQ460.6[医药卫生—中医学]