藏药南寒水石热制炮制工艺研究  

Study on processing technics of Tibetan medicine Nanhanshuishi

作　　者：姜建锋[1] 杜玉枝[1] 魏立新[1] 肖远灿[1] 杨红霞[1] 

机构地区：[1]中国科学院西北高原生物研究所藏药现代化研究中心青海省藏药药理学与安全性评价研究重点实验室,青海西宁810008

出　　处：《中国中药杂志》2011年第6期683-686,共4页China Journal of Chinese Materia Medica

基　　金：国家"重大新药创制"科技重大专项(2009ZX09308-003-11);国家"十一五"科技支撑计划项目(2007BAI48B02-2)

摘　　要：目的:探讨藏药南寒水石的热制最佳炮制工艺。方法:通过文献、典籍记载的查阅及实地走访各藏医院调查了解,对南寒水石热制炮制方法进行归纳总结。据此确定各单因素实验条件并进行正交试验,对不同炮制条件下所得南寒石炮制品中钙(Ca),铁(Fe),锰(Mn),锌(Zn),铜(Cu)元素含量进行测定。结果:粒径10～20 mm,生草乌与火硝比例1∶2,煮沸3h为南寒水石最佳炮制条件。结论:本实验为研究南寒水石热制炮制机制及制定最佳炮制工艺奠定基础。Objective： To study the heat processing technics of Nanhanshuishi. Method： To find the best processing technic, the single factor experiments and orthogonal experiments were designed basing on the processing technics summarized by consulting documents, scriptures and investigating some Tibetan hospitals, meanwhile, the content of Ca, Fe, Mn, Zn, and Cu in the processed Nanhanshuishi in single factor experiments and orthogonal experiments were detected. Result： The best processing technic of Nanhan-shuishi was as follows： Nanhanshuishi was crashed to 10-20 mm in diameter, the ratio of the weight of Aconiti Kusnezoffii Radix and potassium nitrate was 1 ： 2, and the boiling time was 3 h. Conclusion： The work in this article provided a basic processing technic data for clarifying the mechanism of processing and establishing the perfect processing technics of Nanhanshuishi.

关 键 词：南寒水石 炮制 微量元素 正交试验 

分 类 号：R29[医药卫生—民族医学]