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机构地区:[1]上海瑞金医院集团闵行区中心医院感染科,上海201100
出 处:《蚌埠医学院学报》2011年第3期237-239,共3页Journal of Bengbu Medical College
摘 要:目的:探讨支气管肺泡灌洗(BAL)治疗老年肺部感染的临床疗效。方法:将80例老年肺部感染患者随机分为治疗组40例和对照组40例。2组在全身应用抗生素、营养支持、纠正水电解质等治疗基础上,对照组给予常规吸痰治疗及体位引流排痰,治疗组每周行BAL治疗1~2次,比较2组临床表现和影像学变化以评价肺部感染控制情况。结果:治疗后动脉血氧分压、氧合指数治疗组均较对照组明显增高(P<0.01);治疗组缓解率(94.7%)(治愈率+好转率)明显高于对照组缓解率(77.5%)(P<0.05),治疗组抗生素疗程、病灶吸收天数和恢复白细胞计数正常时间均明显低于对照组(P<0.01)。结论:BAL对老年肺部感染是一种经济、安全、有效的治疗方法。Objective:To observe the effect of bronchoalveolar lavage(BAL) on the pneumonia in the elderly. Methods:Eighty elderly patients with pneumonia were divided into BAL group(40 cases) and control group(40 cases).In addition to the routine therapy of antibotics,nutritional support and acid-base balance,the BAL group was adopted to bronchoalveolar lavage(twice a week),and the control group was subjected to sputum aspiration and postural drainage.The clinical presentation and the changes of laboratory and radiological results were compared between the two groups. Results:The PaO2 and the oxygenation index in the BAL group were significantly greater than that in the control group(P〈0.01).The percentage of improvement rate in the BAL group(94.7%) was also significantly greater than that(77.5%) in the control group(P〈0.05),iduration of lesions absorption,the course of antibiotic usage and resuming leukocyte natural times in the BAL group was significantly lower than that in the control group(P〈0.01). Conclusions:The BAL may be an effective method for treatment of pneumonia in the elderly.
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