紫外线照射充氧自血回输并药物治疗白塞综合征  

Ultraviolet blood irradiation and oxygenation for Behcet's syndrome

作　　者：李金星[1] 曹军华[2] 常健[1] 刘小红[1] 孙德英[1] 

机构地区：[1]济南军区总医院 [2]解放军第54784部队教导队卫生所

出　　处：《中华理疗杂志》1999年第5期264-266,共3页Chinese Journal of Physical Therapy

摘　　要：目的　探讨紫外线照射充氧自血回输（ＵＢＩＯ） 治疗白塞综合征（ＢＳ） 的作用机制。方法　动态观察２２ 例ＢＳ患者ＵＢＩＯ 治疗前后血流变学、超氧化物歧化酶（ＳＯＤ） 、谷胱甘肽过氧化物酶（ＧＳＨｐｘ）、脂质过氧化物（ＬＰＯ）、丙二醛（ ＭＤＡ） 、过氧化氢酶（ＣＡＴ） 、肿瘤坏死因子（ＴＮＦ） 、白细胞亚微结构的变化，以药物治疗的１１ 例ＢＳ 患者为对照组作疗效比较。结果　ＵＢＩＯ 后ＢＳ 患者血中ＳＯＤ、ＧＳＨｐｘ、ＣＡＴ 含量较治疗前明显升高，ＬＰＯ、ＭＤＡ、ＴＮＦ及血粘度显著降低，白细胞微绒毛显著增多变粗长，其总有效率（９５ ．９％ ） 明显优于药物组（６３．５ ％ ）。结论　ＵＢＩＯ 治疗ＢＳ的机制可能与减轻ＢＳ患者自由基反应所引起的损害及改善微循环，调节机体免疫功能，提高白细胞杀菌、消炎、吞噬作用有关。Objective The purpose of this paper was to study the mechanism and effect of ultraviolet blood irradiation and oxygenation(UBIO) for Behcet's syndrome(BS).Methods 22 cases with BS were treated with UBIO, while the hemorrheology,SOD,GSHpx,LPO,MDA,CAT, tumor necrosis factor and membrane microstructure of WBC in Behcet' patients were studied before and after UBIO.Another 11 cases with BS as control group were treated with medications.Results After treatment,the total effective rate of UBIO was 95.5% higher than the control group(63.5%),the level of SOD,GSHpx and CAT was odviously raised,the LPO,MDA,tumor necrosis factor and hemorrheology were markedly decreased compared with pre-UBIO.The membrane microstructure of WBC was also changed obviously.Conclusion It is proved that UBIO may reduce the organism damage caused by free radicals,improve the microcirculation,promote the immune function and phagocytosis of WBC.

关 键 词：白塞氏综合征 光量子疗法 UBIO 药物疗法 

分 类 号：R597.905[医药卫生—内科学] R454.2[医药卫生—临床医学]