利伐沙班引起血小板增多  

Thrombocytosis induced by rivaroxaban

作　　者：袁媛[1,2] 李建军[1,2] 陈思远[1,2] 杜良杰[1,2] 

机构地区：[1]首都医科大学康复医学院 [2]北京博爱医院脊柱脊髓神经功能重建科,北京100068

出　　处：《药物不良反应杂志》2010年第6期435-435,共1页Adverse Drug Reactions Journal

摘　　要：1例16岁男性患者,因胸腰椎骨折行手术,术后给予利伐沙班10 mg/d口服。服用前PLT 230×109/L,服用8 d后PLT升至713×109/L。停用利伐沙班,改为那曲肝素钙4 100 IU,1次/12 h皮下注射。血小板计数逐渐下降,换药后19 d PLT降至284×109/L。A 16-year-old boy was undergone a surgery for thoracolumbar vertebra fracture.After operation,he received rivar oxaban 10 mg once daily.His platelet count was 230×109/L before drug adminis tration.However,eight days later,his platelet count increased to 713×109/L.Rivaroxaban was discontinued and changed to SC nadroparin calcium 4 100 IU every 12 hours.His platelet count decreased gradually.Nineteen days later,his pl atelet count was 284×109/L.

关 键 词：利伐沙班 不良反应 血小板增多 

分 类 号：R595.3[医药卫生—内科学]