实时超声造影在乳腺良恶性肿块鉴别诊断中的应用  

Analysis and assessment of real-time contrast-enhanced ultrasonography in the diagnosis of breast masses

作　　者：安姝[1] 刘健[1] 顾鹏[1] 赵兴友[1] 袁顺娴[1] 赵小波[2] 

机构地区：[1]四川省南充市川北医学院附属医院超声科,南充市637000 [2]四川省南充市川北医学院普外三科,南充市637000

出　　处：《中华医学超声杂志（电子版）》2010年第12期44-46,共3页Chinese Journal of Medical Ultrasound(Electronic Edition)

基　　金：四川省科技厅课题(2009JY0097)

摘　　要：目的观察乳腺肿块实时灰阶超声造影增强模式,探讨其在乳腺良恶性肿块鉴别诊断中的价值。方法观察分析30个乳腺肿块的超声造影增强表现,从增强程度、增强模式,增强时肿块边界是否清晰、消退模式等方面,比较研究良恶性肿块血流灌注特征。结果 30个乳腺肿块病理证实良性肿块17个,恶性肿块13个。所有乳腺肿块超声造影均有不同程度增强,其中恶性肿块多表现为3级以上明显增强(69.2%,9/13),增强时边界不清晰不规则,呈放射状(84.6%,11/13),与良性肿块相比,差异有统计学意义(P<0.05)。结论实时灰阶超声造影可以动态观察乳腺肿块内微血管血流灌注,研究良恶性肿块灌注特征有助于提高乳腺良恶性肿块鉴别诊断水平。Objective To investigate the perfusion characteristics of intraductal breast lesion by real-time gray-scale contrast ultrasound and to determine the value of real contrast ultrasound in the diagnosis of breast masses. Methods A total of 30 breast lumps by ultrasound contrast enhancement were observed from the enhanced level. An enhanced mode and enhanced border were observed when the lesion was clear. The perfusion characteristics were compared between the benign and malignant lesions. Results Thirty breast lumps include 17 benign lumps and 13 benign lumps by pathological operation.After injected with the microbubble contrast medium,all breast lumps enhanced to varied extent. And malignant lesions showed significant enhancement for more than 3 grade（69.2%,9/13）.The radial enhancement around lesion were mainly observed in the malignant lesions （P0.05）. Conclusion The microvascular perfusion of breast intraductal lesions can be clearly displayed by real-time gray-scale contrast-enhanced ultrasound. The feasibility of differentiation between benign and malignant lesions according to their perfusion characteristics appears to be promising.

关 键 词：超声检查 造影剂 乳腺肿瘤 

分 类 号：R445.1[医药卫生—影像医学与核医学]