清肺止咳平喘颗粒抗炎和免疫抑制作用初探  

Experimental Studies on Anti-inflammatory and Immunological Effects of Qingfei Zhike Pingchuan Granule

作　　者：甘雨[1] 张宏[1] 石鹤坤[2] 杨文奇[2] 付琳媛[2] 乔敏[1] 孟莉[1] 包玉龙[1] 

机构地区：[1]辽宁省中医药研究院,沈阳110034 [2]辽宁中医药大学,沈阳110032

出　　处：《实验动物科学》2010年第6期13-15,共3页Laboratory Animal Science

摘　　要：目的观察清肺止咳平喘颗粒的抗炎、免疫作用。方法用二甲苯及琼脂建立炎症模型观察清肺止咳平喘颗粒对急性炎症及慢性炎症的作用;从体液免疫和细胞免疫两方面观察清肺止咳平喘颗粒的免疫作用。结果清肺止咳平喘颗粒可明显对抗急性炎症和慢性炎症,抑制体液免疫和细胞免疫。结论清肺止咳平喘颗粒有较好的抗炎和抑制免疫的作用。Objective To observe the anti-inflammatory and immunological effects of Qingfei Zhike Pingchuan Granule.Methods The anti-inflammatory effect of Qingfei Zhike Pingchuan Granule was observed by the acute inflammation and chronic inflammation induced by xylene and agar,and the effect on humoral immunity and cellular immunity was observed by determination of hemolysin level and delayed hypersensitivity induced with 2,4-dinitro-ochlorobenzene.Results Qingfei Zhike Pingchuan Granule could resist the acute inflammation and chronic inflammation,and restrain the humoral immunity and cellular immunity.Conclusion Qingfei Zhike Pingchuan Granule has anti-inflammatory and immunosuppression effects.

关 键 词：清肺止咳平喘颗粒 哮喘 抗炎 免疫 

分 类 号：R95-33[医药卫生—药学]