关联规则分析在中医古代医籍方剂筛选中的应用  

Application of association rules on selecting the prescription from classics of traditional Chinese medicine

作　　者：刘岩[1] 范昕[2] 李康[1] 

机构地区：[1]哈尔滨医科大学卫生统计学教研室,黑龙江省哈尔滨市150001 [2]黑龙江中医药大学医古文教研室

出　　处：《中国医院统计》2010年第4期294-297,共4页Chinese Journal of Hospital Statistics

基　　金：黑龙江省教育厅计划项目（11534131）

摘　　要：目的筛选符合中医理论的方剂，为中药新药研发核心方剂的确定和评价提供科学依据。方法利用关联规则对1521份治疗水气病的中医医家医案进行分析，筛选出核心方剂，剔除不符合中医理论的“方剂”。结果筛选出75个方剂，其中14个经方，同时得到其使用频率顺序。结论结合中医组方特点使用关联规则筛选方剂更为合理和有效。Objective To select prescriptions based on Chinese medicine theory with association rules, and thereby to provide a seientifie evidence for the aecuratc evaluation in developing the core prescriptions of new Chinese drugs. Methods 1521 Chinese medicine records from experts in treating the edema were analyzed using association rules, and the core prescrip- tions conforming with Chinese medicine theory were selected. Results 75 prescriptions were obtained and listed in the rank of usage frequency, in which 14 classical prescriptions had been verified. Conclusion Using association rule combining with the prescription compatibility mechanisms of Chinese medicine, is reasonable and effective in selecting meaningful prescriptions.

关 键 词：中医 方剂筛选 中药配伍 关联规则 

分 类 号：R195.1[医药卫生—卫生统计学]