胰岛素泵在2型糖尿病围手术期的临床观察  

Application of insulin pump to patients of type 2 diabetes in peri-operative period

作　　者：王璇[1] 姜一真[1] 钟建庭[1] 娄明洁[1] 葛秀洁[1] 许瑞元[1] 

机构地区：[1]兰州军区总医院内分泌科,甘肃兰州730050

出　　处：《中国现代医学杂志》2010年第23期3614-3615,3619,共3页China Journal of Modern Medicine

摘　　要：目的观察2型糖尿病(T2DM)患者围手术期胰岛素泵治疗的临床疗效、操作及安全性。方法将拟行手术治疗的T2DM患者分为胰岛素泵持续皮下注射组(CSII组,n=60)和皮下注射胰岛素组(MSII组,n=56)控制围手术期血糖。药物剂量根据血糖波动曲线调整,比较治疗前后患者的全天血糖变化、血糖调整时间、胰岛素用量及术后并发症。结果两组均可有效降低血糖,降糖效果无明显差异(P>0.05),CSII组血糖达标时间、低血糖发生率、胰岛素用量及伤口感染率明显低于MSII组(P<0.05)。CSII组胰岛素用量及术前调整时间均少于MSII组(P<0.05)。结论在2型糖尿病患者围手术期中应用胰岛素泵治疗可以迅速而有效地控制高血糖,减少低血糖及伤口感染的发生,是一种安全有效的方法。【Objective】 To discuss the application value and security of insulin pump in operative period of type 2 diabetes.【Methods】 During the period of peri-operation,type 2 diabetic patients were randomly divided into groups of continuous subcutaneous insulin infusion（CSII,n =60）,and multiple subcutaneous insulin injection（MSII,n =56）.The patients＇ blood glucose modulations,the time of reaching the goal blood glucose,the insulin amount used,the complication and the wound healing situation were compared between both groups before and after treatment.【Results】 The blood glucose was effectively reduced in both groups（P〈 0.01） without obvious difference（P 〉0.05）.The time of controlling the blood glucose after surgery,the insulin amount used,hypoglycemia rate,the complication rate in the CSII group were obviously lower than those in the MSII group（PP〈 0.05）.【Conclusion】 Continuous insulin therapy in the perioperative period can rapidly and effectively control the blood glucose level,and reduce the incidences of hypoglycemia and infectious complications.

关 键 词：糖尿病 胰岛素泵 围手术期 

分 类 号：R619.9[医药卫生—外科学] R587.1[医药卫生—临床医学]